New approaches and procedures for cancer treatment: Current perspectives
DT Debela, SGY Muzazu, KD Heraro… - SAGE open …, 2021 - journals.sagepub.com
Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …
cancer has been a highly complex process. Conventional treatment approaches, such as …
[HTML][HTML] EMT, cancer stem cells and autophagy; The three main axes of metastasis
G Babaei, SGG Aziz, NZZ Jaghi - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Epithelial-mesenchymal transition (EMT) and Cancer stem-like cells (CSCs) are major
factors contributing to the metastasis of cancer cells. Consequently, the signaling pathways …
factors contributing to the metastasis of cancer cells. Consequently, the signaling pathways …
[HTML][HTML] 5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition
Fluorouracil (5-FU) has been an important anti-cancer drug to date. With an increase in the
knowledge of its mechanism of action, various treatment modalities have been developed …
knowledge of its mechanism of action, various treatment modalities have been developed …
Cancer metabolism: phenotype, signaling and therapeutic targets
Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as
aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis …
aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis …
[HTML][HTML] Stem cell programs in cancer initiation, progression, and therapy resistance
Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …
Molecular mechanisms of chemo‐and radiotherapy resistance and the potential implications for cancer treatment
YP Liu, CC Zheng, YN Huang, ML He, WW Xu… - MedComm, 2021 - Wiley Online Library
Cancer is a leading cause of death worldwide. Surgery is the primary treatment approach for
cancer, but the survival rate is very low due to the rapid progression of the disease and …
cancer, but the survival rate is very low due to the rapid progression of the disease and …
Molecular mechanisms of tumor resistance to radiotherapy
Y Wu, Y Song, R Wang, T Wang - Molecular Cancer, 2023 - Springer
Background Cancer is the most prevalent cause of death globally, and radiotherapy is
considered the standard of care for most solid tumors, including lung, breast, esophageal …
considered the standard of care for most solid tumors, including lung, breast, esophageal …
[HTML][HTML] Recent advances in drug delivery systems for targeting cancer stem cells
H Duan, Y Liu, Z Gao, W Huang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
Cancer stem cells and radioresistance: DNA repair and beyond
A Schulz, F Meyer, A Dubrovska, K Borgmann - Cancers, 2019 - mdpi.com
The current preclinical and clinical findings demonstrate that, in addition to the conventional
clinical and pathological indicators that have a prognostic value in radiation oncology, the …
clinical and pathological indicators that have a prognostic value in radiation oncology, the …
[HTML][HTML] The metabolic mechanisms of breast cancer metastasis
L Wang, S Zhang, X Wang - Frontiers in Oncology, 2021 - frontiersin.org
Breast cancer is one of the most common malignancy among women worldwide. Metastasis
is mainly responsible for treatment failure and is the cause of most breast cancer deaths …
is mainly responsible for treatment failure and is the cause of most breast cancer deaths …