Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives

S Anjum, S Ishaque, H Fatima, W Farooq, C Hano… - Pharmaceuticals, 2021 - mdpi.com
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …

Review of the current state of protein aggregation inhibition from a materials chemistry perspective: Special focus on polymeric materials

R Rajan, S Ahmed, N Sharma, N Kumar, A Debas… - Materials …, 2021 - pubs.rsc.org
Protein instability caused by exposure to external additives or severe stress may result in
different diseases. Of these diseases, many are triggered by protein misfolding and …

Nanoparticle size effects in biomedical applications

J Dolai, K Mandal, NR Jana - ACS Applied Nano Materials, 2021 - ACS Publications
Nanoparticle size plays a central role in determining material properties and performance in
biomedical applications. A wide variety of functional nanomaterials and nano-bioconjugates …

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration

P Rusmini, K Cortese, V Crippa, R Cristofani… - Autophagy, 2019 - Taylor & Francis
Macroautophagy/autophagy, a defense mechanism against aberrant stresses, in neurons
counteracts aggregate-prone misfolded protein toxicity. Autophagy induction might be …

Trehalose and its applications in the food industry

A Chen, H Tapia, JM Goddard… - … Reviews in Food …, 2022 - Wiley Online Library
Trehalose is a nonreducing disaccharide composed of two glucose molecules linked by α, α‐
1, 1‐glycosidic bond. It is present in a wide variety of organisms, including bacteria, fungi …

[HTML][HTML] Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

X Niu, J Chen, J Gao - Asian journal of pharmaceutical sciences, 2019 - Elsevier
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,
Huntington disease and amyotrophic lateral sclerosis throw a heavy burden on families and …

Applications of various types of nanomaterials for the treatment of neurological disorders

A Waris, A Ali, AU Khan, M Asim, D Zamel, K Fatima… - Nanomaterials, 2022 - mdpi.com
Neurological disorders (NDs) are recognized as one of the major health concerns globally.
According to the World Health Organization (WHO), neurological disorders are one of the …

Targeting amyloid aggregation: an overview of strategies and mechanisms

S Giorgetti, C Greco, P Tortora, FA Aprile - International journal of …, 2018 - mdpi.com
Amyloids result from the aggregation of a set of diverse proteins, due to either specific
mutations or promoting intra-or extra-cellular conditions. Structurally, they are rich in …

A review of metal and metal-oxide nanoparticle coating technologies to inhibit agglomeration and increase bioactivity for agricultural applications

A Cartwright, K Jackson, C Morgan, A Anderson… - Agronomy, 2020 - mdpi.com
Coatings offer a means to control nanoparticle (NP) size, regulate dissolution, and mitigate
runoff when added to crops through soil. Simultaneously, coatings can enhance particle …

Synthesis and application of trehalose materials

D Vinciguerra, MB Gelb, HD Maynard - JACS Au, 2022 - ACS Publications
Trehalose is a naturally occurring, nonreducing disaccharide that is widely used in the
biopharmaceutical, food, and cosmetic industries due to its stabilizing and cryoprotective …