Molecular self-assembly and supramolecular chemistry of cyclic peptides

Q Song, Z Cheng, M Kariuki, SCL Hall, SK Hill… - Chemical …, 2021 - ACS Publications
This Review focuses on the establishment and development of self-assemblies governed by
the supramolecular interactions between cyclic peptides. The Review first describes the type …

Strategies for fine-tuning the conformations of cyclic peptides

R Jwad, D Weissberger, L Hunter - Chemical Reviews, 2020 - ACS Publications
Cyclic peptides are promising scaffolds for drug development, attributable in part to their
increased conformational order compared to linear peptides. However, when optimizing the …

Recent advances in controlling the internal and external properties of self-assembling cyclic peptide nanotubes and dimers

N Rodríguez-Vázquez, M Amorín… - Organic & Biomolecular …, 2017 - pubs.rsc.org
One of the most powerful strategies for the preparation of nanotubes is based on the
stacking of flat-shaped cyclic peptide components. This strategy allows precise control of the …

Structural and biofunctional insights into the Cyclo (Pro-Pro-Phe-Phe-) Scaffold from experimental and in silico studies: Melanoma and beyond

J Bojarska, M Breza, M Remko, M Czyz… - International Journal of …, 2022 - mdpi.com
Short peptides have great potential as safe and effective anticancer drug leads. Herein, the
influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient …

Non-standard amino acids and peptides: From self-assembly to nanomaterials

F Clerici, E Erba, ML Gelmi, S Pellegrino - Tetrahedron letters, 2016 - Elsevier
The exploitation of peptides in the development of smart nanomaterials is gaining increasing
attention in the last few years. Amino acids are indeed able to drive the self-assembly and …

Wrapping chiral nanoribbons into coiled and condensed microstructures in supramolecular hydrogels

F Wang, H Qiu, C Feng - Advanced Functional Materials, 2020 - Wiley Online Library
Hierarchical self‐assembly of small molecules into supramolecular structures across various
length scales is of prominent importance to deeply understand and mimic the biological …

100th anniversary of macromolecular science viewpoint: user's guide to supramolecular peptide–polymer conjugates

JY Rho, S Perrier - ACS Macro Letters, 2021 - ACS Publications
This Viewpoint highlights the design principles and development of peptide-based
supramolecular polymers. Here we delve deep into the practicalities of synthesizing and …

Parallel and antiparallel cyclic d/l peptide nanotubes

MR Silk, J Newman, JC Ratcliffe, JF White… - Chemical …, 2017 - pubs.rsc.org
Nanotubes made from H-bonded cyclic D/L peptide (CP) subunits have great potential for
the construction of nanomaterials of wide chemical and structural diversity but, to date …

Synthesis of Cyclic γ‐Amino Acids for Foldamers and Peptide Nanotubes

N Rodríguez‐Vázquez, S Salzinger… - European Journal of …, 2013 - Wiley Online Library
Cyclic γ‐amino acids are molecular building blocks of great interest in peptide and foldamer
chemistry, as they allow the preparation of new structures that are not found in Nature. In this …

Membrane-targeted self-assembling cyclic peptide nanotubes

N Rodriguez-Vazquez, H Lionel Ozores… - Current Topics in …, 2014 - ingentaconnect.com
Peptide nanotubes are novel supramolecular nanobiomaterials that have a tubular structure.
The stacking of cyclic components is one of the most promising strategies amongst the …