Dilated cardiomyopathy: genetic determinants and mechanisms
EM McNally, L Mestroni - Circulation research, 2017 - Am Heart Assoc
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
Inherited cardiomyopathies
JA Towbin - Circulation Journal, 2014 - jstage.jst.go.jp
Cardiomyopathies (ie, diseases of the heart muscle) are major causes of morbidity and
mortality. A significant percentage of patients with cardiomyopathies have genetic-based …
mortality. A significant percentage of patients with cardiomyopathies have genetic-based …
[HTML][HTML] Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy
R Roncarati, C Viviani Anselmi, P Krawitz… - European Journal of …, 2013 - nature.com
Familial dilated cardiomyopathy (DCM) is a heterogeneous disease; although 30 disease
genes have been discovered, they explain only no more than half of all cases; in addition …
genes have been discovered, they explain only no more than half of all cases; in addition …
Role of cardiac magnetic resonance in the evaluation of dilated cardiomyopathy: diagnostic contribution and prognostic significance
M Francone - International Scholarly Research Notices, 2014 - Wiley Online Library
Dilated cardiomyopathy (DCM) represents the final common morphofunctional pathway of
various pathological conditions in which a combination of myocyte injury and necrosis …
various pathological conditions in which a combination of myocyte injury and necrosis …
Diagnosis, prevalence, and screening of familial dilated cardiomyopathy
ME Sweet, MRG Taylor, L Mestroni - Expert opinion on orphan …, 2015 - Taylor & Francis
Introduction: Dilated cardiomyopathy (DCM) is the most common cardiomyopathy and
occurs often in families. As an inherited disease, understanding the significance of …
occurs often in families. As an inherited disease, understanding the significance of …
[HTML][HTML] A cost-effectiveness model of genetic testing and periodical clinical screening for the evaluation of families with dilated cardiomyopathy
Purpose To assess the relative cost-effectiveness of cascade genetic testing in
asymptomatic relatives of patients with dilated cardiomyopathy (DCM) compared with …
asymptomatic relatives of patients with dilated cardiomyopathy (DCM) compared with …
[HTML][HTML] Autophagy and inflammasome activation in dilated cardiomyopathy
A Caragnano, A Aleksova, M Bulfoni… - Journal of Clinical …, 2019 - mdpi.com
Background: The clinical outcome of patients affected by dilated cardiomyopathy (DCM) is
heterogeneous, since its pathophysiology is only partially understood. Interleukin 1β levels …
heterogeneous, since its pathophysiology is only partially understood. Interleukin 1β levels …
CoQ10 Function and Role in Heart Failure and Ischemic Heart Disease
A Ayer, P Macdonald, R Stocker - Annual review of nutrition, 2015 - annualreviews.org
Coenzyme Q (CoQ) is an essential lipid of cells present in all cellular compartments. The
functions of CoQ in mitochondrial respiration and as an antioxidant are established …
functions of CoQ in mitochondrial respiration and as an antioxidant are established …
[HTML][HTML] Differential gene expression of cardiac ion channels in human dilated cardiomyopathy
MM Molina-Navarro, E Roselló-Lletí, A Ortega… - PloS one, 2013 - journals.plos.org
Background Dilated cardiomyopathy (DCM) is characterized by idiopathic dilation and
systolic contractile dysfunction of the cardiac chambers. The present work aimed to study the …
systolic contractile dysfunction of the cardiac chambers. The present work aimed to study the …
Sudden cardiac death: A comparative review of humans, dogs and cats
C Brugada-Terradellas, A Hellemans, P Brugada… - The Veterinary …, 2021 - Elsevier
Sudden death is one of the most common causes of death in humans in Western countries.
Approximately 85% of these cases are of cardiac origin. In dogs and cats, sudden cardiac …
Approximately 85% of these cases are of cardiac origin. In dogs and cats, sudden cardiac …