Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment

Y Wang, R Bellomo - Nature Reviews Nephrology, 2017 - nature.com
Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically
important complication in adult patients undergoing open heart surgery, and is associated …

Prevention of acute kidney injury

M Küllmar, A Zarbock, DT Engelman… - Critical Care …, 2020 - criticalcare.theclinics.com
Cardiac surgery–associated acute kidney injury (CSA-AKI) is one of the major complications
after cardiac surgery and independently associated with worse short-term and long-term …

Drug delivery to the brain: how can nanoencapsulated statins be used in the clinic?

F Sonvico, F Zimetti, AR Pohlmann… - Therapeutic …, 2017 - Taylor & Francis
Statins are used for the primary and secondary prevention of cardiovascular disease by
inhibiting cholesterol synthesis in the liver. Statins have also noncholesterol-related effects …

Effect of preoperative moderate-dose statin and duration on acute kidney injury after cardiac surgery: a retrospective cohort study

J Jiang, X Liu, Z Cheng, Q Liu… - Current Medical Research …, 2024 - Taylor & Francis
Background The impact of preoperative statin use on postoperative acute kidney injury (AKI)
is uncertain. We aimed to examine the association of statin therapy before cardiac surgery …

[HTML][HTML] Evaluation of preprocedural statin loading on clinical outcomes in patients undergoing elective percutaneous coronary intervention

UY Sinan, B Keskin Meric, N Bursa… - Frontiers in …, 2024 - frontiersin.org
Background and aim High-dose statin therapy before percutaneous coronary intervention
(PCI) is thought to reduce the occurrence of Peri-procedural Myocardial Infarction (PPMI) …

Evaluation of microvascular endothelial function and capillary density in patients with infective endocarditis using laser speckle contrast imaging and video …

A Barcelos, E Tibirica, C Lamas - Microvascular Research, 2018 - Elsevier
Objective To evaluate the systemic microcirculation of patients with infective endocarditis
(IE). Methods This is a comparative study of patients with definite IE by the modified Duke …

Atorvastatin and blood flow regulate expression of distinctive sets of genes in mouse carotid artery endothelium

S Kumar, S Sur, J Perez, C Demos, DW Kang… - Current Topics in …, 2021 - Elsevier
Hypercholesterolemia is a well-known pro-atherogenic risk factor and statin is the most
effective anti-atherogenic drug that lowers blood cholesterol levels. However, despite …

[HTML][HTML] Shrinking Weibel‐Palade bodies prevents high platelet recruitment in assays using thrombotic thrombocytopenic purpura plasma

F Patella, C Vendramin, O Charles, MA Scully… - Research and Practice …, 2021 - Elsevier
Background Thrombotic thrombocytopenic purpura (TTP), caused by a genetic or
autoimmune‐driven lack of ADAMTS‐13 activity, leads to high levels of the ultra‐large von …

[HTML][HTML] Long-Term preoperative atorvastatin or rosuvastatin use in adult patients before CABG does not increase incidence of postoperative acute kidney injury: A …

V Shvartz, E Khugaeva, Y Kryukov, M Sokolskaya… - Pathophysiology, 2022 - mdpi.com
Background: Acute kidney injury (AKI) is among the expected complications of cardiac
surgery. Statins with pleiotropic anti-inflammatory and antioxidant effects may be effective in …

Management of cardiovascular health in acute leukemia: a national survey

M Durand, K Lacaria, M Sidsworth, MK Davis… - Leukemia & …, 2019 - Taylor & Francis
Cardiovascular (CV) disease is a common comorbidity in acute leukemia (AL) patients and
can be worsened by the use of anthracyclines. Interruptions and underutilization of CV …