CRISPR/Cas9 gene editing: a new approach for overcoming drug resistance in cancer

M Vaghari-Tabari, P Hassanpour… - Cellular & Molecular …, 2022 - Springer
The CRISPR/Cas9 system is an RNA-based adaptive immune system in bacteria and
archaea. Various studies have shown that it is possible to target a wide range of human …

Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics

W Liu, L Li, J Jiang, M Wu, P Lin - Precision clinical medicine, 2021 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …

[HTML][HTML] CRISPR technology: The engine that drives cancer therapy

M Zhang, EA Eshraghian, O Al Jammal, Z Zhang… - Biomedicine & …, 2021 - Elsevier
CRISPR gene editing technology belongs to the third generation of gene editing technology.
Since its discovery, it has attracted the attention of a large number of researchers …

Zinc and respiratory viral infections: important trace element in anti-viral response and immune regulation

F Sadeghsoltani, I Mohammadzadeh, MM Safari… - Biological trace element …, 2021 - Springer
Influenza viruses, respiratory syncytial virus (RSV), and SARS-COV2 are among the most
dangerous respiratory viruses. Zinc is one of the essential micronutrients and is very …

CRISPR/Cas9-mediated gene therapy for glioblastoma: a scoping review

E Begagić, H Bečulić, N Đuzić, A Džidić-Krivić… - Biomedicines, 2024 - mdpi.com
This scoping review examines the use of CRISPR/Cas9 gene editing in glioblastoma (GBM),
a predominant and aggressive brain tumor. Categorizing gene targets into distinct groups …

The CRISPR-Cas system as a tool for diagnosing and treating infectious diseases

J Lou, B Wang, J Li, P Ni, Y Jin, S Chen, Y Xi… - Molecular Biology …, 2022 - Springer
Emerging and relapsing infectious diseases pose a huge health threat to human health and
a new challenge to global public health. Rapid, sensitive and simple diagnostic tools are …

[HTML][HTML] CRISPR-Cas system: a promising diagnostic tool for Covid-19

S Ebrahimi, H Khanbabaei, S Abbasi… - Avicenna journal of …, 2022 - ncbi.nlm.nih.gov
More than a year has passed since the beginning of the 2019 novel coronavirus diseases
(COVID-19) pandemic which has created massive problems globally affecting all aspects of …

The use of CRISPR/Cas9 as a tool to study human infectious viruses

H Lin, G Li, X Peng, A Deng, L Ye, L Shi… - Frontiers in Cellular …, 2021 - frontiersin.org
Clustered regularly interspaced short palindromic repeats (CRISPR) systems are a set of
versatile gene-editing toolkit that perform diverse revolutionary functions in various fields of …

Application of CRISPR/Cas9 technology in cancer treatment: a future direction

AA Rabaan, H AlSaihati, R Bukhamsin… - Current oncology, 2023 - mdpi.com
Gene editing, especially with clustered regularly interspaced short palindromic repeats
associated protein 9 (CRISPR-Cas9), has advanced gene function science. Gene editing's …

The immune system of prokaryotes: potential applications and implications for gene editing

S Liu, H Liu, X Wang, L Shi - Biotechnology Journal, 2024 - Wiley Online Library
Gene therapy has revolutionized the treatment of genetic diseases. Spearheading this
revolution are sophisticated genome editing methods such as TALENs, ZFNs, and CRISPR …