Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

Fungal endocarditis: pathophysiology, epidemiology, clinical presentation, diagnosis, and management

GR Thompson III, JD Jenks, JW Baddley… - Clinical microbiology …, 2023 - Am Soc Microbiol
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

[HTML][HTML] Impact of climate change and natural disasters on fungal infections

D Seidel, S Wurster, JD Jenks, H Sati… - The Lancet …, 2024 - thelancet.com
The effects of climate change and natural disasters on fungal pathogens and the risks for
fungal diseases remain incompletely understood. In this literature review, we examined how …

Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease

M Hoenigl, A Arastehfar, MC Arendrup… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …

Salvage treatment for invasive aspergillosis and mucormycosis: challenges, recommendations and future considerations

M Egger, R Bellmann, R Krause, J Boyer… - Infection and drug …, 2023 - Taylor & Francis
Invasive mold diseases are devastating systemic infections which demand meticulous care
in selection, dosing, and therapy monitoring of antifungal drugs. Various circumstances …

The dog as a sentinel and animal model for coccidioidomycosis

AJ Ferguson, GR Thompson, D Bruyette… - Medical …, 2024 - academic.oup.com
Coccidioidomycosis is a potentially fatal fungal disease of humans and animals that follows
inhalation of Coccidioides spp. arthroconidia in the environment. The disease in dogs …

[HTML][HTML] Epidemiology of Coccidioidomycosis in the Veterans Health Administration, 2013–2022

C Lucero-Obusan, R Deka, P Schirmer, G Oda… - Journal of Fungi, 2023 - mdpi.com
We describe the epidemiology of coccidioidomycosis among a national cohort of Veterans.
Using electronic health record data from adults tested for coccidioidomycosis between 1 …

[HTML][HTML] Social determinants of health as drivers of fungal disease

JD Jenks, J Prattes, S Wurster, R Sprute, D Seidel… - …, 2023 - thelancet.com
Disparities in social determinants of health (SDOH) play a significant role in causing health
inequities globally. The physical environment, including housing and workplace …

[HTML][HTML] Multilocus sequence typing of Candida albicans oral isolates reveals high genetic relatedness of mother-child dyads in early life

N Alkhars, N Al Jallad, TT Wu, J Xiao - Plos one, 2024 - journals.plos.org
Candida albicans is a pathogenic fungus recently recognized for its role in severe early
childhood caries development (S-ECC). C. albicans oral colonization begins at birth, but the …

[HTML][HTML] The Known and Unknown “Knowns” of Human Susceptibility to Coccidioidomycosis

AP Hsu - Journal of Fungi, 2024 - mdpi.com
Coccidioidomycosis occurs after inhalation of airborne spores of the endemic, dimorphic
fungus, Coccidioides. While the majority of individuals resolve the infection without coming …