The physiological functions of human peroxisomes

RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

A new pathway for mitochondrial quality control: mitochondrial‐derived vesicles

A Sugiura, GL McLelland, EA Fon, HM McBride - The EMBO journal, 2014 - embopress.org
The last decade has been marked by tremendous progress in our understanding of the cell
biology of mitochondria, with the identification of molecules and mechanisms that regulate …

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

AM Valm, S Cohen, WR Legant, J Melunis… - Nature, 2017 - nature.com
The organization of the eukaryotic cell into discrete membrane-bound organelles allows for
the separation of incompatible biochemical processes, but the activities of these organelles …

Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

A Sugiura, S Mattie, J Prudent, HM McBride - Nature, 2017 - nature.com
Peroxisomes function together with mitochondria in a number of essential biochemical
pathways, from bile acid synthesis to fatty acid oxidation. Peroxisomes grow and divide from …

[HTML][HTML] The peroxisome-mitochondria connection: how and why?

M Fransen, C Lismont, P Walton - International journal of molecular …, 2017 - mdpi.com
Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …

[HTML][HTML] Human disorders of peroxisome metabolism and biogenesis

HR Waterham, S Ferdinandusse… - Biochimica Et Biophysica …, 2016 - Elsevier
Peroxisomes are dynamic organelles that play an essential role in a variety of cellular
catabolic and anabolic metabolic pathways, including fatty acid alpha-and beta-oxidation …

Peroxisomes take shape

JJ Smith, JD Aitchison - Nature reviews Molecular cell biology, 2013 - nature.com
Peroxisomes carry out various oxidative reactions that are tightly regulated to adapt to the
changing needs of the cell and varying external environments. Accordingly, they are …

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis

R Hua, D Cheng, É Coyaud, S Freeman… - Journal of Cell …, 2017 - rupress.org
Lipid exchange between the endoplasmic reticulum (ER) and peroxisomes is necessary for
the synthesis and catabolism of lipids, the trafficking of cholesterol, and peroxisome …

[HTML][HTML] ORP1L mediated PI (4) P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division

M Boutry, PK Kim - Nature Communications, 2021 - nature.com
Mitochondrial division is not an autonomous event but involves multiple organelles,
including the endoplasmic reticulum (ER) and lysosomes. Whereas the ER drives the …

Plant peroxisomes: biogenesis and function

J Hu, A Baker, B Bartel, N Linka, RT Mullen… - The Plant …, 2012 - academic.oup.com
Peroxisomes are eukaryotic organelles that are highly dynamic both in morphology and
metabolism. Plant peroxisomes are involved in numerous processes, including primary and …