Protective Mechanism of Leucine and Isoleucine against H2O2‐Induced Oxidative Damage in Bovine Mammary Epithelial Cells

S Wu, X Liu, L Cheng, D Wang, G Qin… - Oxidative Medicine …, 2022 - Wiley Online Library
Leucine and isoleucine possess antioxidative and anti‐inflammatory properties. However,
their underlying protective mechanisms against oxidative damage remain unknown …

A novel defect of peroxisome division due to a homozygous non-sense mutation in the PEX11β gene

MS Ebberink, J Koster, G Visser… - Journal of medical …, 2012 - jmg.bmj.com
Background Peroxisomes are organelles that proliferate continuously and play an
indispensable role in human metabolism. Consequently, peroxisomal gene defects can …

[HTML][HTML] Protein import machineries of peroxisomes

R Rucktäschel, W Girzalsky, R Erdmann - Biochimica et Biophysica Acta …, 2011 - Elsevier
Peroxisomes are a class of structurally and functionally related organelles present in almost
all eukaryotic cells. The importance of peroxisomes for human life is highlighted by severe …

An ER‐peroxisome tether exerts peroxisome population control in yeast

B Knoblach, X Sun, N Coquelle, A Fagarasanu… - The EMBO …, 2013 - embopress.org
Eukaryotic cells compartmentalize biochemical reactions into membrane‐enclosed
organelles that must be faithfully propagated from one cell generation to the next. Transport …

How tails guide tail-anchored proteins to their destinations

N Borgese, S Brambillasca, S Colombo - Current opinion in cell biology, 2007 - Elsevier
A large group of diverse, functionally important, and differently localized transmembrane
proteins shares a particular membrane topology, consisting of a cytosolic N-terminal region …

The ASH1–PEX16 regulatory pathway controls peroxisome biogenesis for appressorium-mediated insect infection by a fungal pathogen

L Wang, Y Lai, J Chen, X Cao… - Proceedings of the …, 2023 - National Acad Sciences
Entomopathogenic fungi infect insects by penetrating through the cuticle into the host body.
To breach the host cuticle, some fungal pathogens produce specialized infection cells called …

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p-and Pex16p-dependent pathway

T Matsuzaki, Y Fujiki - The Journal of cell biology, 2008 - rupress.org
Two distinct pathways have recently been proposed for the import of peroxisomal membrane
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …

Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains

B Schrul, RR Kopito - Nature cell biology, 2016 - nature.com
Lipid droplets (LDs) are endoplasmic reticulum (ER)-derived lipid storage organelles
uniquely encapsulated by phospholipid monolayers. LD membrane proteins are embedded …

The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder

E Nuebel, JT Morgan, S Fogarty, JM Winter… - EMBO …, 2021 - embopress.org
Peroxisomal biogenesis disorders (PBDs) are genetic disorders of peroxisome biogenesis
and metabolism that are characterized by profound developmental and neurological …

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

JG Pemberton, YJ Kim, J Humpolickova… - Journal of Cell …, 2020 - rupress.org
Phosphatidylinositol (PI) is an essential structural component of eukaryotic membranes that
also serves as the common precursor for polyphosphoinositide (PPIn) lipids. Despite the …