Several nitrogen heterocyclic analogues have been applied to clinical practice, and about
75% of drugs approved by the FDA contain at least a heterocyclic moiety. Thus, nitrogen …

Five-membered heterocycles are essential structural components in various antibacterial
drugs; the physicochemical properties of a five-membered heterocycle can play a crucial …

Herein, a photoinduced palladium-catalyzed annulation of 1, 3-dienes with bifunctional
halognated alkylamines has been developed, offering a facile route to access a broad range …

Direct C3-functionalization of quinoxalin-2 (1H)-ones is a convenient way to develop new
and sustainable strategies, which are important for natural product and drug modification …

Azetidine substituent group has a wide range of application in organic chemistry and
medical field. In this study, a novel azetidine derivative and its reaction mechanism has been …

A visible‐light‐catalyzed formal [3+ 2] annulation‐aromatization reaction for the synthesis of
various substituted imidazo [2, 1‐a] isoquinolines from amidines with stabilized …

Malaria is a widespread infectious disease, causing nearly 247 million cases in 2021. The
absence of a broadly effective vaccine and rapidly decreasing effectiveness of most of the …

The synthesis and biological assessment of novel multi-functionalized pyrrolidine-containing
benzenesulfonamides were reported along with their antimicrobial, antifungal, CAs …

We presented a cascade transformation of N, N‐diallylamines and fluoroalkyl iodides into
various functionalized fluoroalkylated pyrrolidines through a visible light‐induced synthetic …

Molecular complexity plays an increasingly important role in the modern pharmaceutical
industry. Setting up multiple stereogenic centers in privileged substructures may give rise to …