The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

Osteosarcoma is the most common primary bone sarcoma and is often diagnosed in the 2nd–
3rd decades of life. Response to the aggressive and highly toxic neoadjuvant methotrexate …

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant
free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis …

Cancer, a major world public health problem, is associated with chemotherapy treatments
whose administration leads to secondary concerns, such as oral mucositis (OM). The OM …

The potential role of 'leaky gut'or reduced barrier function with increased intestinal
permeability has been considered an important factor in intestinal and extraintestinal …

Circular RNAs (circRNAs) are a new series of noncoding RNAs (ncRNAs) that have been
reported to be expressed in eukaryotic cells and have a variety of biological functions in the …

Background: As one of the few modifiable risk factors, the importance of dietary patterns for
both disease prevention and treatment outcome in pediatric oncology has gained increasing …

We conducted a systematic review and meta‐analysis of randomized controlled trials
(RCTs) that investigated glutamine efficacy in preventing and alleviating radiation‐induced …

Impairment of intestinal barrier function is linked to certain pathologies and to aging, and can
be a cause of bacterial infections, systemic and hepatic inflammation, food allergies, and …

Background and Aims Malnutrition is prevalent among head and neck cancer (HNC)
patients and leads to undesirable outcomes such as reduced treatment response and …