Nephrotoxicity and renal pathophysiology: a contemporary perspective

LMA Barnett, BS Cummings - Toxicological Sciences, 2018 - academic.oup.com
The kidney consists of numerous cell types organized into the nephron, which is the basic
functional unit of the kidney. Any stimuli that induce loss of these cells can induce kidney …

Optimization strategies of mesenchymal stem cell-based therapy for acute kidney injury

Z Fu, Y Zhang, X Geng, K Chi, C Liu, C Song… - Stem Cell Research & …, 2023 - Springer
Considering the high prevalence and the lack of targeted pharmacological management of
acute kidney injury (AKI), the search for new therapeutic approaches for it is in urgent …

Curcumin exerts a protective effect against premature ovarian failure in mice

Z Yan, Y Dai, H Fu, Y Zheng, D Bao… - Journal of …, 2018 - jme.bioscientifica.com
This study was designed to investigate the protective effect of curcumin against d-galactose
(d-gal)-induced premature ovarian failure (POF) in mice. A mouse POF model was induced …

Effect of curcumin on glycerol-induced acute kidney injury in rats

J Wu, X Pan, H Fu, Y Zheng, Y Dai, Y Yin, Q Chen… - Scientific reports, 2017 - nature.com
The aim of this study was to investigate the protective role and underlying mechanisms of
curcumin on glycerol-induced acute kidney injury (AKI) in rats. Glycerol (10 ml/kg BW, 50 …

The antioxidant curcumin postpones ovarian aging in young and middle-aged mice

SH Azami, H Nazarian, MA Abdollahifar… - Reproduction …, 2020 - CSIRO Publishing
Reproductive senescence is accompanied by a reduced number and quality of ovarian
follicles in response to the accumulation of free radicals and the process of apoptosis …

Nrf2/HO-1 as a therapeutic target in renal fibrosis

EHM Hassanein, IM Ibrahim, EK Abd-Alhameed… - Life Sciences, 2023 - Elsevier
Chronic kidney disease (CKD) is one of the most prevalent chronic diseases and affects
between 10 and 14% of the world's population. The World Health Organization estimates …

Extracellular vesicles for acute kidney injury in preclinical rodent models: a meta-analysis

C Liu, J Wang, J Hu, B Fu, Z Mao, H Zhang… - Stem Cell Research & …, 2020 - Springer
Abstract Introduction Extracellular vesicles (EVs), especially stem cell-derived EVs, have
emerged as a potential novel therapy for acute kidney injury (AKI). However, their effects …

Mesenchymal stem cells ameliorate cuprizone-induced demyelination by targeting oxidative stress and mitochondrial dysfunction

E Shiri, P Pasbakhsh, M Borhani‑Haghighi… - Cellular and molecular …, 2021 - Springer
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. The main causes of MS disease progression, demyelination, and tissue damage are …

Curcumin-loaded super-paramagnetic iron oxide nanoparticle affects on apoptotic factors expression and histological changes in a prepubertal mouse model of …

SMF Abhari, R Khanbabaei, NH Roodbari, K Parivar… - Life sciences, 2020 - Elsevier
Aims This study investigated the effects of curcumin-loaded super-paramagnetic iron oxide
(Fe 3 O 4) nanoparticles (NPs)(SPIONs) on histological parameters and apoptosis-inducing …

Artificial kidney capsule packed with mesenchymal stem cell-laden hydrogel for the treatment of rhabdomyolysis-induced acute kidney injury

Z Fu, Y Chu, X Geng, Y Ma, K Chi, C Song… - ACS Biomaterials …, 2022 - ACS Publications
Acute kidney injury (AKI) has emerged as a major public health problem affecting millions of
people worldwide without specific and satisfactory therapies due to the lack of an effective …