Molecular mechanisms of atopic dermatitis pathogenesis
J Sroka-Tomaszewska, M Trzeciak - International journal of molecular …, 2021 - mdpi.com
Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic
feature is persistent itching of the skin. The chronic, relapsing course of the disease …
feature is persistent itching of the skin. The chronic, relapsing course of the disease …
Update on atopic dermatitis
T Torres, E Ferreira, M Gonçalo… - Acta medica …, 2019 - repositorio.chporto.pt
With an increasing prevalence during the past decades, atopic dermatitis has become a
global health issue. A literature search following a targeted approach was undertaken to …
global health issue. A literature search following a targeted approach was undertaken to …
Efficacy and safety of dupilumab in adolescents with uncontrolled moderate to severe atopic dermatitis: a phase 3 randomized clinical trial
EL Simpson, AS Paller, EC Siegfried… - JAMA …, 2020 - jamanetwork.com
Importance Adolescents with atopic dermatitis (AD) have high disease burden negatively
affecting quality of life, with limited treatment options. The efficacy and safety of dupilumab, a …
affecting quality of life, with limited treatment options. The efficacy and safety of dupilumab, a …
Multiple roles for cytokines in atopic dermatitis: from pathogenic mediators to endotype-specific biomarkers to therapeutic targets
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases, which
generally presents with intense itching and recurrent eczematous lesions. AD affects up to …
generally presents with intense itching and recurrent eczematous lesions. AD affects up to …
A review of safety outcomes from clinical trials of baricitinib in rheumatology, dermatology and COVID-19
Baricitinib is an oral, selective inhibitor of Janus kinase (JAK) 1/JAK2 that transiently and
reversibly inhibits many proinflammatory cytokines. This mechanism is a key mediator in a …
reversibly inhibits many proinflammatory cytokines. This mechanism is a key mediator in a …
Overlapping features of psoriasis and atopic dermatitis: from genetics to immunopathogenesis to phenotypes
YC Tsai, TF Tsai - International Journal of Molecular Sciences, 2022 - mdpi.com
Psoriasis (PSO) and atopic dermatitis (AD) were once considered to be mutually exclusive
diseases, but gradually regarded as a spectrum of disease. Shared genetic loci of both …
diseases, but gradually regarded as a spectrum of disease. Shared genetic loci of both …
[HTML][HTML] Atopic eczema in adulthood and risk of depression and anxiety: a population-based cohort study
Background Atopic eczema is a common and debilitating condition associated with
depression and anxiety, but the nature of this association remains unclear. Objective To …
depression and anxiety, but the nature of this association remains unclear. Objective To …
Atopic dermatitis: pathomechanisms and lessons learned from novel systemic therapeutic options
T Bieber, AS Paller, K Kabashima… - Journal of the …, 2022 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, heterogenous, inflammatory skin disorder associated
with a high skin‐related health burden, typically starting in childhood and often persisting …
with a high skin‐related health burden, typically starting in childhood and often persisting …
Efficacy of Bifidobacterium longum alone or in multi-strain probiotic formulations during early life and beyond
The significance of Bifidobacterium to human health can be appreciated from its early
colonization of the neonatal gut, where Bifidobacterium longum represents the most …
colonization of the neonatal gut, where Bifidobacterium longum represents the most …
The role of the environmental risk factors in the pathogenesis and clinical outcome of atopic dermatitis
D Bonamonte, A Filoni, M Vestita… - BioMed research …, 2019 - Wiley Online Library
Atopic dermatitis (AD) prevalence is rising worldwide. Literature data suggest the incidence
of AD in developing countries is gradually getting close to that of developed ones, in which …
of AD in developing countries is gradually getting close to that of developed ones, in which …