Active transport between the nucleus and cytoplasm involves primarily three classes of
macromolecules: substrates, adaptors, and receptors. Some transport substrates bind …

In eukaryotic organisms, DNA replication and RNA biogenesis occur in the cell nucleus,
whereas protein synthesis occurs in the cytoplasm. Integration of these activities depends on …

CRM1 is distantly related to receptors that mediate nuclear protein import and was
previously shown to interact with the nuclear pore complex. Overexpression of CRM1 in …

Among proteins that accumulate in plants in response to dehydrative forces or low
temperature, dehydrins (late embryogenesis abundant [Lea] D11 family) have been the most …

Active nuclear import of protein is controlled by nuclear localization signals (NLSs), but
nuclear export is not understood well. Nuclear trafficking of the catalytic (C) subunit of cAMP …

HIV-1 Rev protein directs nuclear export of pre-mRNAs and mRNAs containing its binding
site, the Rev response element (RRE). To define how Rev acts, we used conjugates …

To control agonist-induced nuclear translocation of transcription factor κB (NF-κB) in intact
cells, cell-permeable synthetic peptides were devised. Their import into intact cells was …

The cap structure that is characteristic of all polymerase‐II‐transcribed RNAs has been
shown to play an important role in many aspects of RNA metabolism including RNA …

We report the cDNA deduced primary structure of a wheat germ agglutinin-reactive nuclear
pore complex (NPC) protein of rat. The protein, termed Nup98 (for nucleoporin of 98 kDa) …

The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that binds DNA
in the form of a heterodimer with the Ahr nuclear translocator (hypoxia-inducible factor 1β) …