Inflammatory bowel disease (IBD), mainly including ulcerative colitis (UC) and Crohn's
disease (CD), is an autoimmune gastrointestinal disease characterized by chronic …

The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

A complex pathogenesis involving several physiological systems is theorized to underline
the development of depressive disorders. Depression is accompanied by circadian …

Abstract Shenling Baizhu San has beneficial effects on the metabolism of the gut microbiota,
however, the mechanisms underlying microbiota metabolites mediated anti-inflammation …

Melatonin interacts in multiple ways with microglia, both directly and, via routes of crosstalk
with astrocytes and neurons, indirectly. These effects of melatonin are of relevance in terms …

Clinical depression is a multifactorial disorder and one of the leading causes of disability
worldwide. The alterations in tryptophan metabolism such as changes in the levels of …

Background Inflammatory osteolysis after total joint replacement (TJR) may cause implant
failure, periprosthetic fractures, and be a severe threat to global public health. Our previous …

Diseases caused by pathogenic bacteria in animals (eg, bacterial pneumonia, meningitis
and sepsis) and plants (eg, bacterial wilt, angular spot and canker) lead to high prevalence …

Traumatic brain injury (TBI) is a common cause of disability and mortality, affecting millions
of people every year. The neuroinflammation and immune response post-TBI initially have …

Depression has become one of the most commonly prevalent neuropsychiatric disorders,
and the main characteristics of depression are sleep disorders and melatonin secretion …