The past two decades have witnessed a paradigm shift in the treatment of squamous cell
carcinoma of the head and neck. Innovation in chemotherapy, radiotherapy and surgery has …

The treatment of head and neck cancer has been at the forefront of novel therapeutic
paradigms. The introduction of drugs that interact with selective biologic pathways in the …

This is a comment on" Phase II multicenter study of the epidermal growth factor receptor
antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the …

New advances are being incorporated into the radiochemotherapy treatment of squamous
cell carcinoma of the head and neck. Although the overall prognosis is poor in advanced …

The care of the patient with squamous cell carcinoma of the head and neck (SCCHN)
requires a multidisciplinary approach. For many years, radiotherapy following surgery was …

New cytotoxic and molecular-targeted therapies of head and n... : Current Opinion in Oncology
New cytotoxic and molecular-targeted therapies of head and neck tumors : Current Opinion in …

Recent knowledge about the intermediate steps and final consequences of ligand-
dependent epidermal growth factor receptor (EGFR) activation has clearly supported the …

A well-coordinated interaction between extracellular signals and intracellular response
forms the basis of life within multicellular organisms, with growth factors playing a crucial …

Cytotoxic chemotherapy has only yielded modest gains in survival in lung cancer in the past
decade. However, the development of agents targeting specific signaling pathways that …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in both
men and women. Despite the introduction of the newer cytotoxic agents in NSCLC treatment …