Curcumin and colorectal cancer: An update and current perspective on this natural medicine

W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

The molecular hallmarks of the serrated pathway in colorectal cancer

FDE De Palma, V D'argenio, J Pol, G Kroemer… - Cancers, 2019 - mdpi.com
Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different
subtypes that differ in their clinical and prognostic features. In the past decade, in addition to …

Vitamin D and cancer: an historical overview of the epidemiology and mechanisms

A Muñoz, WB Grant - Nutrients, 2022 - mdpi.com
This is a narrative review of the evidence supporting vitamin D's anticancer actions. The first
section reviews the findings from ecological studies of cancer with respect to indices of solar …

Probiotics and colon cancer

L Drago - Microorganisms, 2019 - mdpi.com
Literature has recently highlighted the enormous scientific interest on the relationship
between the gut microbiota and colon cancer, and how the use of some selected probiotics …

Lysates of Lactobacillus acidophilus combined with CTLA-4-blocking antibodies enhance antitumor immunity in a mouse colon cancer model

Q Zhuo, B Yu, J Zhou, J Zhang, R Zhang, J Xie… - Scientific reports, 2019 - nature.com
Previous reports have suggested that many gut microbiomes were associated with the
development of colorectal cancer (CRC), and could modulate response to numerous forms …

[HTML][HTML] Evaluation and comparison of short chain fatty acids composition in gut diseases

E Niccolai, S Baldi, F Ricci, E Russo… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND An altered (dysbiosis) and unhealthy status of the gut microbiota is usually
responsible for a reduction of short chain fatty acids (SCFAs) concentration. SCFAs obtained …

E-cadherin beyond structure: a signaling hub in colon homeostasis and disease

AC Daulagala, MC Bridges, A Kourtidis - International journal of …, 2019 - mdpi.com
E-cadherin is the core component of epithelial adherens junctions, essential for tissue
development, differentiation, and maintenance. It is also fundamental for tissue barrier …

Driver gene mutations and epigenetics in colorectal cancer

H Raskov, JH Søby, J Troelsen, RD Bojesen… - Annals of …, 2020 - journals.lww.com
Objective: The majority of patients with colorectal cancer are diagnosed with locally
advanced and/or disseminated disease, and treatment options include surgery in …

Alterations in the gut microbiome and suppression of histone deacetylases by resveratrol are associated with attenuation of colonic inflammation and protection …

HR Alrafas, PB Busbee, KN Chitrala… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is known to significantly increase the risk for development
of colorectal cancer (CRC), suggesting inflammation and cancer development are closely …

The pivotal role of the gut microbiome in colorectal cancer

R Siddiqui, A Boghossian, AM Alharbi, H Alfahemi… - Biology, 2022 - mdpi.com
Simple Summary Colorectal cancer is a common form of cancer observed globally. It is
thought that the gut microbiome may play a pivotal role in the development and progression …