[HTML][HTML] Chlamydia trachomatis genital infections

CM O'Connell, ME Ferone - Microbial cell, 2016 - ncbi.nlm.nih.gov
Etiology, transmission and protection: Chlamydia trachomatis is the leading cause of
bacterial sexually transmitted infection (STI) globally. However, C. trachomatis also causes …

Evolution, phylogeny, and molecular epidemiology of Chlamydia

A Nunes, JP Gomes - Infection, Genetics and Evolution, 2014 - Elsevier
The Chlamydiaceae are a family of obligate intracellular bacteria characterized by a unique
biphasic developmental cycle. It encompasses the single genus Chlamydia, which involves …

[HTML][HTML] Plasmid metagenome reveals high levels of antibiotic resistance genes and mobile genetic elements in activated sludge

T Zhang, XX Zhang, L Ye - PloS one, 2011 - journals.plos.org
The overuse or misuse of antibiotics has accelerated antibiotic resistance, creating a major
challenge for the public health in the world. Sewage treatment plants (STPs) are considered …

[HTML][HTML] Development of a Transformation System for Chlamydia trachomatis: Restoration of Glycogen Biosynthesis by Acquisition of a Plasmid Shuttle Vector

Y Wang, S Kahane, LT Cutcliffe, RJ Skilton… - PLoS …, 2011 - journals.plos.org
Chlamydia trachomatis remains one of the few major human pathogens for which there is no
transformation system. C. trachomatis has a unique obligate intracellular developmental …

Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes

L Song, JH Carlson, WM Whitmire, L Kari… - Infection and …, 2013 - Am Soc Microbiol
Chlamydia trachomatis causes chronic inflammatory diseases of the eye and genital tract
and has global medical importance. The chlamydial plasmid plays an important role in the …

Unity in Variety—The Pan-Genome of the Chlamydiae

A Collingro, P Tischler, T Weinmaier… - Molecular biology …, 2011 - academic.oup.com
Chlamydiae are evolutionarily well-separated bacteria that live exclusively within eukaryotic
host cells. They include important human pathogens such as Chlamydia trachomatis as well …

Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome

M Albrecht, CM Sharma, R Reinhardt… - Nucleic acids …, 2010 - academic.oup.com
Chlamydia trachomatis is an obligate intracellular pathogenic bacterium that has been
refractory to genetic manipulations. Although the genomes of several strains have been …

[HTML][HTML] Sensitive and rapid detection of Chlamydia trachomatis by recombinase polymerase amplification directly from urine samples

K Krõlov, J Frolova, O Tudoran, J Suhorutsenko… - The Journal of Molecular …, 2014 - Elsevier
Chlamydia trachomatis is the most common sexually transmitted human pathogen. Infection
results in minimal to no symptoms in approximately two-thirds of women and therefore often …

Plasmid-encoded Pgp3 is a major virulence factor for Chlamydia muridarum to induce hydrosalpinx in mice

Y Liu, Y Huang, Z Yang, Y Sun, S Gong… - Infection and …, 2014 - Am Soc Microbiol
Hydrosalpinx induction in mice by Chlamydia muridarum infection, a model that has been
used to study C. trachomatis pathogenesis in women, is known to depend on the cryptic …

Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches

BD Nguyen, RH Valdivia - Proceedings of the National …, 2012 - National Acad Sciences
Chlamydia trachomatis, a pathogen responsible for diseases of significant clinical and
public health importance, remains poorly characterized because of its intractability to routine …