The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …

Several epidemiological studies have identified diabetes as a risk factor for colorectal
cancer (CRC). The potential pathophysiological mechanisms of this association include …

Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe
COVID-19. However, the immune signatures associated with immunopathology are poorly …

Immune checkpoint blockade (ICB) is a powerful approach for cancer therapy although good
responses are only observed in a fraction of cancer patients. Breast cancers caused by …

Tumor‐associated macrophages (TAMs) are an important part of tumor microenvironment
(TME) and play a key role in TME, participating in the process of tumor occurrence, growth …

Abstract Background Neutrophil extracellular traps (NETs) are considered significant
contributors to cancer progression, especially metastasis. However, it is still unclear whether …

Abstract S100A8 and S100A9 are Ca 2+ binding proteins that belong to the S100 family.
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …

Cutaneous T cell lymphoma (CTCL) is characterized by the accumulation of malignant T
cells in the skin. However, advanced CTCL pathophysiology remains elusive and …

Fusobacterium nucleatum (Fn) has been considered as a significant contributor in promoting
colorectal carcinoma (CRC) development by suppressing host anti-tumor immunity. Recent …

Tumor‐associated macrophages (TAMs) are crucial components of the tumor
microenvironment. They play vital roles in hepatocellular carcinoma (HCC) progression …