Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
Cytokine storm is a phenomenon characterized by strong elevated circulating cytokines that
most often occur after an overreactive immune system is activated by an acute systemic …

Boosting regulatory T cell function for the treatment of autoimmune diseases–That's only half the battle!

J Schlöder, F Shahneh, FJ Schneider… - Frontiers in …, 2022 - frontiersin.org
Regulatory T cells (Treg) represent a subset of specialized T cells that are essential for the
regulation of immune responses and maintenance of peripheral tolerance. Once activated …

Revisiting regulatory T cells as modulators of innate immune response and inflammatory diseases

Q Ou, R Power, MD Griffin - Frontiers in Immunology, 2023 - frontiersin.org
Regulatory T cells (Treg) are known to be critical for the maintenance of immune
homeostasis by suppressing the activation of auto-or allo-reactive effector T cells through a …

Plant Polyphenols Attenuate DSS-induced Ulcerative Colitis in Mice via Antioxidation, Anti-inflammation and Microbiota Regulation

H Chen, Y Li, J Wang, T Zheng, C Wu, M Cui… - International Journal of …, 2023 - mdpi.com
The pathogenesis of ulcerative colitis (UC) is associated with inflammation, oxidative stress,
and gut microbiota imbalance. Although most researchers have demonstrated the …

HNRNPC suppresses tumor immune microenvironment by activating Treg cells promoting the progression of prostate cancer

Y Cheng, L Li, X Wei, F Xu, X Huang, F Qi… - Cancer …, 2023 - Wiley Online Library
Immune microenvironment could affect the biological progress in prostate cancer (PCa)
through N6 methyl adenosine (m6A) methylation. The purpose of this study was to …

Roles of type 1 regulatory T (Tr1) cells in allergen-specific immunotherapy

M Matsuda, T Terada, K Kitatani, R Kawata… - Frontiers in …, 2022 - frontiersin.org
Allergen-specific immunotherapy (AIT) is the only causative treatment for allergic diseases
by modification of the immune response to allergens. A key feature of AIT is to induce …

Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients

AD Hoffmann, SE Weinberg, S Swaminathan… - Clinical …, 2023 - Elsevier
Over two years into the COVID-19 pandemic, the human immune response to SARS-CoV-2
during the active disease phase has been extensively studied. However, the long-term …

Expression of IL-37 induces a regulatory T-cell-like phenotype and function in Jurkat cells

DG Osborne, J Domenico, M Fujita - Cells, 2022 - mdpi.com
The anti-inflammatory cytokine interleukin-37 (IL-37) plays a key role in inhibiting innate and
adaptive immunity. Past results have shown that IL-37 is elevated in human Treg cells …

Sepsis-associated encephalopathy: From pathophysiology to clinical management

Y Hong, P Chen, J Gao, Y Lin, L Chen… - International …, 2023 - Elsevier
Sepsis-associated encephalopathy, which presents as delirium and coma, is a significant
complication of sepsis characterized by acute brain dysfunction. The presence of …

Cross talk between human regulatory T cells and antigen‐presenting cells: Lessons for clinical applications

CM Wardell, KN MacDonald… - European journal of …, 2021 - Wiley Online Library
Regulatory T cells (Tregs) have a critical role in maintaining self‐tolerance and immune
homeostasis. There is much interest in using Tregs as a cell therapy to re‐establish …