Personalized cancer nanomedicine: Overcoming biological barriers for intracellular delivery of biopharmaceuticals

AM López‐Estévez, P Lapuhs… - Advanced …, 2024 - Wiley Online Library
The success of personalized medicine in oncology relies on using highly effective and
precise therapeutic modalities such as small interfering RNA (siRNA) and monoclonal …

Mitochondria deregulations in cancer offer several potential targets of therapeutic interventions

C Musicco, A Signorile, V Pesce… - International Journal of …, 2023 - mdpi.com
Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …

Graphene-Based Nanomaterials for Photothermal Therapy in Cancer Treatment

DF Báez - Pharmaceutics, 2023 - mdpi.com
Graphene-based nanomaterials (GBNMs), specifically graphene oxide (GO) and reduced
graphene oxide (rGO), have shown great potential in cancer therapy owing to their …

[HTML][HTML] Evaluation of biogenically synthesized MgO NPs anticancer activity against breast cancer cells

MR Khan, NO Alafaleq, AK Ramu, K Alhosaini… - Saudi Journal of …, 2024 - Elsevier
Background Magnesium is recognized to have pharmacological potential, and its
nanoformulation is anticipated to offer significant therapeutic effects, particularly against …

Current perspectives and trends in nanoparticle drug delivery systems in breast cancer: bibliometric analysis and review

S Sun, Y Wang, X Gao, H Wang, L Zhang… - … in Bioengineering and …, 2023 - frontiersin.org
The treatment of breast cancer (BC) is a serious challenge due to its heterogeneous nature,
multidrug resistance (MDR), and limited therapeutic options. Nanoparticle-based drug …

QbD-optimized, phospholipid-based elastic nanovesicles for the effective delivery of 6-Gingerol: a promising topical option for pain-related disorders

M Ghazwani, MH Alqarni, U Hani, A Alam - International Journal of …, 2023 - mdpi.com
In this study, elastic nanovesicles, constructed of phospholipids optimized by Quality by
Design (QbD), release 6-gingerol (6-G), a natural chemical that may alleviate osteoporosis …

Deep eutectic solvent based self-healable, stretchable and injectable eutectogels: A versatile platform for breast cancer treatment

N Parsana, H Ukani, OA El Seoud, A Al-Ghamdi… - Chemical Engineering …, 2024 - Elsevier
Recent focus is on developing cancer treatments that overcome challenges of high-dose
chemotherapy, providing improved safety, effectiveness, and site-specific targeting through …

Stimuli-Responsive Polymeric Nanomedicine for Enhanced Cancer Immunotherapy

CH Kim, ES Lee, H Ko, S Son, SH Kim… - Chemistry of …, 2024 - ACS Publications
Cancer immunotherapy, aimed at reinvigorating the immune system to induce a lasting
anticancer response, has emerged as a promising approach for counteracting the evasive …

Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review

M Arafat, M Sakkal, R Beiram, S AbuRuz - Pharmaceuticals, 2024 - mdpi.com
Cancer continues to pose one of the most critical challenges in global healthcare. Despite
the wide array of existing cancer drugs, the primary obstacle remains in selectively targeting …

A Direct Comparison of Peptide Drug Delivery Systems Based on the Use of Hybrid Calcium Phosphate/Chitosan Nanoparticles versus Unmixed Calcium Phosphate …

E Popova, V Tikhomirova, O Beznos… - International Journal of …, 2023 - mdpi.com
Nanocarriers provide a number of undeniable advantages that could improve the
bioavailability of active agents for human, animal, and plant cells. In this study, we compared …