Lipid composition of the cancer cell membrane

W Szlasa, I Zendran, A Zalesińska, M Tarek… - Journal of bioenergetics …, 2020 - Springer
Cancer cell possesses numerous adaptations to resist the immune system response and
chemotherapy. One of the most significant properties of the neoplastic cells is the altered …

The multi-factorial nature of clinical multidrug resistance in cancer

YG Assaraf, A Brozovic, AC Gonçalves… - Drug resistance …, 2019 - Elsevier
Curative cancer therapy remains a major challenge particularly in cancers displaying
multidrug resistance (MDR). The MDR phenotype is characterized by cross-resistance to a …

Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy

T Yong, X Zhang, N Bie, H Zhang, X Zhang, F Li… - Nature …, 2019 - nature.com
Developing biomimetic nanoparticles without loss of the integrity of proteins remains a major
challenge in cancer chemotherapy. Here, we develop a biocompatible tumor-cell …

Targeted liposomal drug delivery: a nanoscience and biophysical perspective

Y Liu, KMC Bravo, J Liu - Nanoscale horizons, 2021 - pubs.rsc.org
Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

J Yang, A Griffin, Z Qiang, J Ren - Signal transduction and targeted …, 2022 - nature.com
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

[HTML][HTML] Enzyme-triggered deep tumor penetration of a dual-drug nanomedicine enables an enhanced cancer combination therapy

L Gu, Z Duan, X Li, X Li, Y Li, X Li, G Xu, P Gao… - Bioactive Materials, 2023 - Elsevier
Cancer cells could be eradicated by promoting generation of excessive intracellular reactive
oxygen species (ROS) via emerging nanomedicines. However, tumor heterogeneity and …

Advanced material modulation of nutritional and phytohormone status alleviates damage from soybean sudden death syndrome

C Ma, J Borgatta, BG Hudson, AA Tamijani… - Nature …, 2020 - nature.com
Abstract Customized Cu3 (PO4) 2 and CuO nanosheets and commercial CuO nanoparticles
were investigated for micronutrient delivery and suppression of soybean sudden death …

[HTML][HTML] Cell membrane modulation as adjuvant in cancer therapy

S Zalba, TLM Ten Hagen - Cancer treatment reviews, 2017 - Elsevier
Cancer is a complex disease involving numerous biological processes, which can exist in
parallel, can be complementary, or are engaged when needed and as such can replace …

Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy

W Xia, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …

Cholesterol modulates the liposome membrane fluidity and permeability for a hydrophilic molecule

S Kaddah, N Khreich, F Kaddah, C Charcosset… - Food and Chemical …, 2018 - Elsevier
The effect of cholesterol (CHOL) content on the permeability and fluidity of
dipalmitoylphosphatidylcholine (DPPC) liposome membrane was investigated. Liposomes …