Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies

S Muhammad, T Fan, Y Hai, Y Gao, J He - Molecular Cancer, 2023 - Springer
Abstract Interleukin-2 (IL-2) and its receptor (IL-2R) are essential in orchestrating immune
responses. Their function and expression in the tumor microenvironment make them …

Manganese-Enriched Zinc Peroxide Functional Nanoparticles for Potentiating Cancer Immunotherapy

M Zhou, S Liang, D Liu, K Ma, K Yun, J Yao, Y Peng… - Nano Letters, 2023 - ACS Publications
Immunotherapies have shown high clinical success, however, the therapeutical efficacy is
largely restrained by insufficient immune activation and an immunosuppressive …

Titanium‐based nanoarchitectures for sonodynamic therapy‐involved multimodal treatments

A Maleki, M Seyedhamzeh, M Yuan, T Agarwal… - Small, 2023 - Wiley Online Library
Sonodynamic therapy (SDT) has considerably revolutionized the healthcare sector as a
viable noninvasive therapeutic procedure. It employs a combination of low‐intensity …

Nanomaterials: breaking through the bottleneck of tumor immunotherapy

Y Kang, S Li - International Journal of Biological Macromolecules, 2023 - Elsevier
Immunotherapy exerts its excellent anti-tumor effects by stimulating and enhancing the
immune response of the body, and has become another important class of anti-tumor …

Artificial intelligence in cancer immunotherapy: applications in neoantigen recognition, antibody design and immunotherapy response prediction

T Li, Y Li, X Zhu, Y He, Y Wu, T Ying, Z Xie - Seminars in Cancer Biology, 2023 - Elsevier
Cancer immunotherapy is a method of controlling and eliminating tumors by reactivating the
body's cancer-immunity cycle and restoring its antitumor immune response. The increased …

mRNA delivery systems for cancer immunotherapy: lipid nanoparticles and beyond

ME Senti, LG Del Valle, RM Schiffelers - Advanced Drug Delivery Reviews, 2024 - Elsevier
Abstract mRNA-based vaccines are emerging as a promising alternative to standard cancer
treatments and the conventional vaccines. Moreover, the FDA-approval of three nucleic acid …

Metal-Based Nanoparticles for Cancer Metalloimmunotherapy

IH Suliman, K Kim, W Chen, Y Kim, JH Moon, S Son… - Pharmaceutics, 2023 - mdpi.com
Although the promise of cancer immunotherapy has been partially fulfilled with the
unprecedented clinical success of several immunotherapeutic interventions, some issues …

Global serum profiling: an opportunity for earlier cancer detection

A Sala, JM Cameron, PM Brennan, EJ Crosbie… - Journal of Experimental …, 2023 - Springer
The advances in cancer research achieved in the last 50 years have been remarkable and
have provided a deeper knowledge of this disease in many of its conceptual and …

TRAIL-sensitizing effects of flavonoids in cancer

A Luiz-Ferreira, T Pacifico, ÁC Cruz, F Laudisi… - International Journal of …, 2023 - mdpi.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) represents a promising
anticancer agent, as it selectively induces apoptosis in transformed cells without altering the …