SMC (structural maintenance of chromosomes) protein complexes are an evolutionarily
conserved family of motor proteins that hold sister chromatids together and fold genomes …

Condensins are large protein complexes that play a central role in chromosome
organization and segregation in the three domains of life. They display highly characteristic …

The long chromosomal DNAs of cells are organized into loop domains much larger in size
than individual DNA-binding enzymes, presenting the question of how formation of such …

Protein complexes built of structural maintenance of chromosomes (SMC) and kleisin
subunits, including cohesin, condensin and the Smc5/6 complex, are master organizers of …

Type II topoisomerases are ubiquitous enzymes in all branches of life that can alter DNA
superhelicity and unlink double-stranded DNA segments during processes such as …

Condensins are multisubunit protein complexes that play a fundamental role in the structural
and functional organization of chromosomes in the three domains of life. Most eukaryotic …

The canonical condensin complex (henceforth condensin I) plays an essential role in mitotic
chromosome assembly and segregation from yeast to humans. We report here the …

The structural maintenance of chromosomes (SMC) family is a growing family of
chromosomal ATPases. The founding class of SMC protein complexes, condensins, plays a …

SMC condensin complexes play a central role in compacting and resolving replicated
chromosomes in virtually all organisms, yet how they accomplish this remains elusive. In …

▪ Abstract Protein complexes consisting of s tructural m aintenance of c hromosomes (SMC)
and kleisin subunits are crucial for the faithful segregation of chromosomes during cell …