Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring
AD Stephens, J Haase, L Vicci, RM Taylor… - Journal of Cell …, 2011 - rupress.org
Sister chromatid cohesion provides the mechanistic basis, together with spindle
microtubules, for generating tension between bioriented chromosomes in metaphase …
microtubules, for generating tension between bioriented chromosomes in metaphase …
Mutation of YCS4, a Budding Yeast Condensin Subunit, Affects Mitotic and Nonmitotic Chromosome Behavior
The budding yeast YCS4 gene encodes a conserved regulatory subunit of the condensin
complex. We isolated an allele of this gene in a screen for mutants defective in sister …
complex. We isolated an allele of this gene in a screen for mutants defective in sister …
[HTML][HTML] A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein
MI Fousteri, AR Lehmann - The EMBO journal, 2000 - embopress.org
In Schizosaccharomyces pombe, rad18 is an essential gene involved in the repair of DNA
damage produced by ionizing radiation and in tolerance of UV‐induced DNA damage. The …
damage produced by ionizing radiation and in tolerance of UV‐induced DNA damage. The …
The evolution of SMC proteins: phylogenetic analysis and structural implications
N Cobbe, MMS Heck - Molecular biology and evolution, 2004 - academic.oup.com
The SMC proteins are found in nearly all living organisms examined, where they play crucial
roles in mitotic chromosome dynamics, regulation of gene expression, and DNA repair. We …
roles in mitotic chromosome dynamics, regulation of gene expression, and DNA repair. We …
Crystal structure of the SMC head domain: an ABC ATPase with 900 residues antiparallel coiled-coil inserted
J Löwe, SC Cordell, F van den Ent - Journal of molecular biology, 2001 - Elsevier
SMC (structural maintenance of chromosomes) proteins are large coiled-coil proteins
involved in chromosome condensation, sister chromatid cohesion, and DNA double-strand …
involved in chromosome condensation, sister chromatid cohesion, and DNA double-strand …
[HTML][HTML] Bimodal activation of SMC ATPase by intra-and inter-molecular interactions
M Hirano, DE Anderson, HP Erickson, T Hirano - The EMBO journal, 2001 - embopress.org
Structural maintenance of chromosomes (SMC) proteins play fundamental roles in higher-
order chromosome dynamics from bacteria to humans. It has been proposed that the …
order chromosome dynamics from bacteria to humans. It has been proposed that the …
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
Condensin complexes have central roles in the three-dimensional organization of
chromosomes during cell divisions, but how they interact with chromatin to promote …
chromosomes during cell divisions, but how they interact with chromatin to promote …
Suppression of chromosome segregation defects of Escherichia coli muk mutants by mutations in topoisomerase I
JA Sawitzke, S Austin - Proceedings of the National …, 2000 - National Acad Sciences
Escherichia coli muk mutants are temperature-sensitive and produce anucleate cells. A
spontaneously occurring mutation was found in a ΔmukB∷ kan mutant strain that …
spontaneously occurring mutation was found in a ΔmukB∷ kan mutant strain that …
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis
Background: Faithful segregation of the genome during mitosis requires interphase
chromatin to be condensed into well-defined chromosomes. Chromosome condensation …
chromatin to be condensed into well-defined chromosomes. Chromosome condensation …
Real-time detection of single-molecule DNA compaction by condensin I
TR Strick, T Kawaguchi, T Hirano - Current biology, 2004 - cell.com
Background: Condensin is thought to contribute to large-scale DNA compaction during
mitotic chromosome assembly. It remains unknown, however, how the complex reconfigures …
mitotic chromosome assembly. It remains unknown, however, how the complex reconfigures …