[HTML][HTML] Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Depression in neurodegenerative diseases: Common mechanisms and current treatment options

CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Meta‐analysis of early nonmotor features and risk factors for Parkinson disease

AJ Noyce, JP Bestwick, L Silveira‐Moriyama… - Annals of …, 2012 - Wiley Online Library
Objective: To evaluate the association between diagnosis of Parkinson disease (PD) and
risk factors or early symptoms amenable to population‐based screening. Methods: A …

Identifying prodromal Parkinson's disease: pre‐motor disorders in Parkinson's disease

RB Postuma, D Aarsland, P Barone… - Movement …, 2012 - Wiley Online Library
Increasing recognition that Parkinson's disease (PD) may start outside of the substantia
nigra has led to a rapidly expanding effort to define prodromal stages of PD, before motor …

Depression in older adults

A Fiske, JL Wetherell, M Gatz - Annual review of clinical …, 2009 - annualreviews.org
Depression is less prevalent among older adults than among younger adults, but it can have
serious consequences. More than half of cases represent a first onset in later life. Although …

Depression and Parkinson's disease: current knowledge

L Marsh - Current neurology and neuroscience reports, 2013 - Springer
Depressive disturbances are common in patients with Parkinson's disease (PD) and
influence many other clinical aspects of the disease. In addition to causing inherent …

Depression in Parkinson disease—epidemiology, mechanisms and management

D Aarsland, S Påhlhagen, CG Ballard, U Ehrt… - Nature Reviews …, 2012 - nature.com
Depression occurs in around 35% of patients with Parkinson disease (PD) and is often
persistent. Symptoms of depression can be evident in individuals at the time of diagnosis …

The scientific and clinical basis for the treatment of Parkinson disease (2009)

CW Olanow, MB Stern, K Sethi - Neurology, 2009 - AAN Enterprises
Parkinson disease (PD) is an age-related neurodegenerative disorder that affects as many
as 1–2% of persons aged 60 years and older. With the aging of the population, the …

[HTML][HTML] The concept of prodromal Parkinson's disease

P Mahlknecht, K Seppi… - Journal of Parkinson's …, 2015 - content.iospress.com
Parkinson's disease (PD) is currently clinically defined by a set of cardinal motor features
centred on the presence of bradykinesia and at least one additional motor symptom out of …

Impaired mitochondrial function in psychiatric disorders

H Manji, T Kato, NA Di Prospero, S Ness… - Nature reviews …, 2012 - nature.com
Major psychiatric illnesses such as mood disorders and schizophrenia are chronic, recurrent
mental illnesses that affect the lives of millions of individuals. Although these disorders have …