[HTML][HTML] New insights and potential therapeutic targeting of CB2 cannabinoid receptors in CNS disorders

BG Kibret, H Ishiguro, Y Horiuchi, ES Onaivi - International journal of …, 2022 - mdpi.com
The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …

[HTML][HTML] HGF and MET: from brain development to neurological disorders

C Desole, S Gallo, A Vitacolonna… - Frontiers in Cell and …, 2021 - frontiersin.org
Hepatocyte growth factor (HGF) and its tyrosine kinase receptor, encoded by the MET
cellular proto-oncogene, are expressed in the nervous system from pre-natal development …

Mesenchymal stem cells: Biological characteristics and application in disease therapy

S Lou, Y Duan, H Nie, X Cui, J Du, Y Yao - Biochimie, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells. In addition to the capacity for
self-renewal and multipotential differentiation, MSCs also have the following characteristics …

[HTML][HTML] Intravenous administration of human mesenchymal stem cells derived from adipose tissue and umbilical cord improves neuropathic pain via suppression of …

K Miyano, M Ikehata, K Ohshima, Y Yoshida, Y Nose… - PLoS …, 2022 - journals.plos.org
Mesenchymal stem cells (MSCs), which are isolated from adipose tissue (AD-MSCs),
umbilical cord (UC-MSCs), or bone marrow, have therapeutic potential including anti …

Evaluation of Edaravone effects on the differentiation of human adipose derived stem cells into oligodendrocyte cells in multiple sclerosis disease in rats

M Bakhtiari, N Ghasemi, H Salehi, N Amirpour… - Life sciences, 2021 - Elsevier
Aims Among all the treatments for Multiple Sclerosis, stem cell transplantation, such as
ADSCs, has attracted a great deal of scientific attention. On the other hand, Edaravone, as …

[HTML][HTML] Potential role of cannabinoid type 2 receptors in neuropsychiatric and neurodegenerative disorders

H Ishiguro, BG Kibret, Y Horiuchi, ES Onaivi - Frontiers in Psychiatry, 2022 - frontiersin.org
The endocannabinoid system (ECS) is composed of the two canonical receptor subtypes;
type-1 cannabinoid (CB1R) and type 2 receptor (CB2R), endocannabinoids (eCBs) and …

[HTML][HTML] The impact of cannabinoid type 2 receptors (CB2Rs) in neuroprotection against neurological disorders

Q Xin, F Xu, DH Taylor, J Zhao, J Wu - Acta Pharmacologica Sinica, 2020 - nature.com
Cannabinoids have long been used for their psychotropic and possible medical properties
of symptom relief. In the past few years, a vast literature shows that cannabinoids are …

[HTML][HTML] Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia

T Xu, X Li, Y Guo, E Uhlin, L Holmberg, S Mitra… - …, 2022 - thelancet.com
Background Post-traumatic syringomyelia (PTS) affects patients with chronic spinal cord
injury (SCI) and is characterized by progressive deterioration of neurological symptoms. To …

Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases

R Al‐kharboosh, JJ Perera, A Bechtle… - Clinical and …, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by the gradual decline and irreversible loss
of cognitive functions and CNS structures. As therapeutic recourse stagnates …

[HTML][HTML] Therapeutic aspects of mesenchymal stem cell-based cell therapy with a focus on human amniotic epithelial cells in multiple sclerosis: a mechanistic review

R ArefNezhad, H Motedayyen… - … Journal of Stem Cells, 2021 - synapse.koreamed.org
Multiple sclerosis (MS) is an inflammatory disease of central nervous system (CNS). The
mmune system plays an important role in its pathogenesis. Current treatments are unable to …