Acinetobacter baumannii Antibiotic Resistance Mechanisms

I Kyriakidis, E Vasileiou, ZD Pana, A Tragiannidis - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to
public health by causing severe and invasive (mostly nosocomial) infections linked with high …

A journey from structure to function of bacterial lipopolysaccharides

F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Polymyxins and bacterial membranes: a review of antibacterial activity and mechanisms of resistance

C Ayoub Moubareck - Membranes, 2020 - mdpi.com
Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to
their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic …

Acinetobacter baumannii: An Ancient Commensal with Weapons of a Pathogen

M Sarshar, P Behzadi, D Scribano, AT Palamara… - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is regarded as a life-threatening pathogen associated with
community-acquired and nosocomial infections, mainly pneumonia. The rise in the number …

Colistin Resistance in Acinetobacter baumannii: Molecular Mechanisms and Epidemiology

K Novović, B Jovčić - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide
spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the …

In Vitro Activity of Sulbactam-Durlobactam against Global Isolates of Acinetobacter baumannii-calcoaceticus Complex Collected from 2016 to 2021

JA Karlowsky, MA Hackel, SM McLeod… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Sulbactam-durlobactam is a β-lactam-β-lactamase inhibitor combination designed to treat
serious Acinetobacter baumannii-calcoaceticus complex (ABC) infections, including …

Immunoinformatics-guided designing of epitope-based subunit vaccine from Pilus assembly protein of Acinetobacter baumannii bacteria

SR Mahapatra, J Dey, A Jaiswal, R Roy, N Misra… - Journal of …, 2022 - Elsevier
Acinetobacter baumannii, a prominent pathogen responsible for chronic infections in the
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …

Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches

J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …

Bacterial infections and cancer: exploring this association and its implications for cancer patients

K Yusuf, V Sampath, S Umar - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial infections are common in the etiology of human diseases owing to the ubiquity of
bacteria. Such infections promote the development of periodontal disease, bacterial …