Mitochondria are intracellular organelles involved in energy production, cell metabolism and
cell signaling. They are essential not only in the process of ATP synthesis, lipid metabolism …

Rheumatoid arthritis (RA) is a systemic and heterogeneous autoimmune disease with
symmetrical polyarthritis as its critical clinical manifestation. The basic cause of autoimmune …

Stem cell-based therapy has drawn attention for enhancing the osseointegration efficiency
after joint replacement in the rheumatoid arthritis (RA). However, therapeutic efficacy of this …

Infiltration of inflammatory cells, especially the M1 macrophages that secrete various types of
inflammation cytokines, play crucial roles in the pathogenesis of rheumatoid arthritis (RA) …

Constructing nanomaterials mimicking the coordination environments of natural enzymes
may achieve biomimetic catalysis. Here we construct a two-dimensional (2D) metal-organic …

Imbalance of macrophage polarization characterized by an increase in the percentage of
pro‐inflammatory M1 macrophages and a decrease in anti‐inflammatory M2 macrophages …

Arthritis typically involves recurrence and progressive worsening at specific predilection
sites, but the checkpoints between remission and persistence remain unknown. Here, we …

Poor O2 supply to the infiltrated immune cells in the joint synovium of rheumatoid arthritis
(RA) up-regulates hypoxia-inducible factor (HIF-1α) expression and induces reactive oxygen …

Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …