Developmental disruptions of the dorsal striatum in autism spectrum disorder
Autism spectrum disorder (ASD) is an increasingly prevalent neurodevelopmental condition
that is characterized by social and communication deficits as well as patterns of restricted …
that is characterized by social and communication deficits as well as patterns of restricted …
Bridging the translational gap: what can synaptopathies tell us about autism?
CJ Molloy, J Cooke, NJF Gatford… - Frontiers in Molecular …, 2023 - frontiersin.org
Multiple molecular pathways and cellular processes have been implicated in the
neurobiology of autism and other neurodevelopmental conditions. There is a current focus …
neurobiology of autism and other neurodevelopmental conditions. There is a current focus …
Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid
S D'Antoni, S Schiavi, V Buzzelli, S Giuffrida, A Feo… - …, 2023 - Springer
Rationale Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized
by impaired social interaction and restricted/stereotyped behavior. Prenatal exposure to …
by impaired social interaction and restricted/stereotyped behavior. Prenatal exposure to …
[HTML][HTML] Metabotropic glutamate receptors (mGluRs) in epileptogenesis: an update on abnormal mGluRs signaling and its therapeutic implications
L Huang, W Xiao, Y Wang, J Li, J Gong… - Neural Regeneration …, 2024 - journals.lww.com
Epilepsy is a neurological disorder characterized by high morbidity, high recurrence, and
drug resistance. Enhanced signaling through the excitatory neurotransmitter glutamate is …
drug resistance. Enhanced signaling through the excitatory neurotransmitter glutamate is …
Glutamate levels of the right and left anterior cingulate cortex in autistics adults
F Briend, L Barantin, H Cléry, JP Cottier… - Progress in Neuro …, 2023 - Elsevier
Abstract Background The neurobiology of Autism Spectrum Disorder (ASD) is still unknown.
Alteration in glutamate metabolism might translate into an imbalance of the …
Alteration in glutamate metabolism might translate into an imbalance of the …
The 'PSILAUT'protocol: an experimental medicine study of autistic differences in the function of brain serotonin targets of psilocybin
TP Whelan, E Daly, NA Puts, P Smith, C Allison… - BMC psychiatry, 2024 - Springer
Background The underlying neurobiology of the complex autism phenotype remains
obscure, although accumulating evidence implicates the serotonin system and especially …
obscure, although accumulating evidence implicates the serotonin system and especially …
Metabotropic glutamate receptor genetic variants and peripheral receptor expression affects trait scores of autistic probands
N Dutta, M Chatterjee, S Saha, S Sinha… - Scientific Reports, 2024 - nature.com
Glutamate (Glu) is important for memory and learning. Hence, Glu imbalance is speculated
to affect autism spectrum disorder (ASD) pathophysiology. The action of Glu is mediated …
to affect autism spectrum disorder (ASD) pathophysiology. The action of Glu is mediated …
Analysis of single nucleotide polymorphisms of the metabotropic glutamate receptors in a transgender population
R Fernández, K Ramírez… - Frontiers in …, 2024 - frontiersin.org
Introduction Gender incongruence (GI) is characterized by a marked incongruence between
an individual's experienced/expressed gender and the assigned sex at birth. It includes …
an individual's experienced/expressed gender and the assigned sex at birth. It includes …
Epigenetic underpinnings of the autistic mind: Histone modifications and prefrontal excitation/inhibition imbalance
YA Fard, EN Sadeghi, Z Pajoohesh… - American Journal of …, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) is complex neurobehavioral condition influenced by several
cellular and molecular mechanisms that are often concerned with synaptogenesis and …
cellular and molecular mechanisms that are often concerned with synaptogenesis and …
癫痫与代谢型谷氨酸受体: 异常mGluRs 信号转导及其治疗意义的最新进展
L Huang, W Xiao, Y Wang, J Li, J Gong, E Tu… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
研究表明, 癫痫可能是由体内兴奋性和抑制性神经递质的相对不平衡引起. 其中,
谷氨酸作为哺乳动物中枢神经系统中的重要兴奋性神经递质, 通过激活离子型谷氨酸受体和代谢 …
谷氨酸作为哺乳动物中枢神经系统中的重要兴奋性神经递质, 通过激活离子型谷氨酸受体和代谢 …