[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

Omicron variant of SARS‐CoV‐2: genomics, transmissibility, and responses to current COVID‐19 vaccines

Y Araf, F Akter, Y Tang, R Fatemi… - Journal of medical …, 2022 - Wiley Online Library
Currently, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has spread
worldwide as an Omicron variant. This variant is a heavily mutated virus and designated as …

Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of SARS-CoV-2 emerged in November 2021 and
is rapidly spreading among the human population. Although recent reports reveal that the …

Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement

M McCallum, N Czudnochowski, LE Rosen, SK Zepeda… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern evades antibody-mediated immunity that comes from vaccination or infection with …

Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients

CH GeurtsvanKessel, D Geers, KS Schmitz… - Science …, 2022 - science.org
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …

[HTML][HTML] Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination

K Röltgen, SCA Nielsen, O Silva, SF Younes… - Cell, 2022 - cell.com
During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been
deployed globally. We investigated whether antibodies stimulated by mRNA vaccination …

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

YJ Park, D Pinto, AC Walls, Z Liu, A De Marco… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …

Emergence of SARS-CoV-2 Omicron (B. 1.1. 529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

R Khandia, S Singhal, T Alqahtani, MA Kamal… - Environmental …, 2022 - Elsevier
Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and
mutating continuously, giving rise to various variants with variable degrees of infectivity and …

[HTML][HTML] T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

V Naranbhai, A Nathan, C Kaseke, C Berrios, A Khatri… - Cell, 2022 - cell.com
Summary The SARS-CoV-2 Omicron variant (B. 1.1. 529) contains mutations that mediate
escape from antibody responses, although the extent to which these substitutions in spike …