Horizontal gene transfer among host-associated microbes

JM de Sousa, M Lourenço, I Gordo - Cell Host & Microbe, 2023 - cell.com
Horizontal gene transfer is an important evolutionary force, facilitating bacterial diversity. It is
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …

Selfish, promiscuous and sometimes useful: how mobile genetic elements drive horizontal gene transfer in microbial populations

M Haudiquet, JM de Sousa… - … Transactions of the …, 2022 - royalsocietypublishing.org
Horizontal gene transfer (HGT) drives microbial adaptation but is often under the control of
mobile genetic elements (MGEs) whose interests are not necessarily aligned with those of …

The defense island repertoire of the Escherichia coli pan-genome

D Hochhauser, A Millman, R Sorek - PLoS genetics, 2023 - journals.plos.org
It has become clear in recent years that anti-phage defense systems cluster non-randomly
within bacterial genomes in so-called “defense islands”. Despite serving as a valuable tool …

Drivers and consequences of bacteriophage host range

D Holtappels, P Alfenas-Zerbini… - FEMS Microbiology …, 2023 - academic.oup.com
Bacteriophages are obligate parasites of bacteria characterized by the breadth of hosts that
they can infect. This “host range” depends on the genotypes and morphologies of the phage …

Identification and characterization of thousands of bacteriophage satellites across bacteria

JAM de Sousa, A Fillol-Salom, JR Penadés… - Nucleic acids …, 2023 - academic.oup.com
Bacteriophage–bacteria interactions are affected by phage satellites, elements that exploit
phages for transfer between bacteria. Satellites can encode defense systems, antibiotic …

The never-ending battle between lactic acid bacteria and their phages

C Philippe, JK Cornuault, AG de Melo… - FEMS Microbiology …, 2023 - academic.oup.com
Over the past few decades, the interest in lactic acid bacteria (LAB) has been steadily
growing. This is mainly due to their industrial use, their health benefits as probiotic bacteria …

Inhibitors of bacterial immune systems: discovery, mechanisms and applications

D Mayo-Muñoz, R Pinilla-Redondo… - Nature Reviews …, 2024 - nature.com
To contend with the diversity and ubiquity of bacteriophages and other mobile genetic
elements, bacteria have developed an arsenal of immune defence mechanisms. Bacterial …

Marine viral particles reveal an expansive repertoire of phage-parasitizing mobile elements

JM Eppley, SJ Biller, E Luo, A Burger… - Proceedings of the …, 2022 - National Acad Sciences
Phage satellites are mobile genetic elements that propagate by parasitizing bacteriophage
replication. We report here the discovery of abundant and diverse phage satellites that were …

[PDF][PDF] A widespread family of phage-inducible chromosomal islands only steals bacteriophage tails to spread in nature

N Alqurainy, L Miguel-Romero, JM de Sousa, J Chen… - Cell Host & Microbe, 2023 - cell.com
Phage satellites are genetic elements that couple their life cycle to that of helper phages
they parasitize, interfering with phage packaging through the production of small capsids …

Simultaneous entry as an adaptation to virulence in a novel satellite-helper system infecting Streptomyces species

T deCarvalho, E Mascolo, SM Caruso… - The ISME …, 2023 - academic.oup.com
Satellites are mobile genetic elements that are dependent upon the replication machinery of
their helper viruses. Bacteriophages have provided many examples of satellite nucleic acids …