Exercise and cellular innate immune function.

JA Woods, JM Davis, JA Smith… - Medicine and Science in …, 1999 - europepmc.org
Epidemiological evidence suggests a link between the intensity of exercise and infectious
and neoplastic disease. One likely way by which exercise exerts its effect on cancer and …

NK cells and apoptosis

HS Warren, MJ Smyth - Immunology and cell biology, 1999 - Wiley Online Library
Natural killer (NK) cells are a cell of the innate immune system that play an important role in
the early response to viral infections and tumours. Natural killer cells are cytolytic, and …

Mig, the monokine induced by interferon-γ, promotes tumor necrosis in vivo

C Sgadari, JM Farber, AL Angiolillo… - Blood, The Journal …, 1997 - ashpublications.org
Mig, the monokine induced by interferon-γ, is a CXC chemokine active as a chemoattractant
for activated T cells. Mig is related functionally to interferon-inducible protein 10 (IP-10), with …

Cytokine-induced apoptosis of human natural killer cells identifies a novel mechanism to regulate the innate immune response

ME Ross, MA Caligiuri - Blood, The Journal of the American …, 1997 - ashpublications.org
Abstract Interferon-γ (IFN-γ) is critical for an effective innate immune response against
infection. A combination of interleukins (ILs) derived from activated T cells (IL-2) and …

Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12

C Kanegane, C Sgadari, H Kanegane… - Journal of leukocyte …, 1998 - academic.oup.com
The mechanisms by which interleukin-12 (IL-12) exerts antitumor effects have been difficult
to dissect. In this study, we examined the potential contribution of the chemokines interferonγ …

Detection of dead cells and measurement of cell killing by flow cytometry

MA King - Journal of immunological methods, 2000 - Elsevier
A flow cytometer can quickly perform numerous quantitative, sensitive measurements on
each individual cell within a large, heterogeneous population. The modern commercially …

Fratricide of natural killer cells dressed with tumor-derived NKG2D ligand

K Nakamura, M Nakayama… - Proceedings of the …, 2013 - National Acad Sciences
The natural killer group 2 membrane D (NKG2D) activating receptor plays crucial roles not
only in host defense against tumors and viral infections, but also in autoimmune diseases …

Interleukin 2 and interleukin 15 differentially predispose natural killer cells to apoptosis mediated by endothelial and tumour cells

L Rodella, L Zamai, R Rezzani, M Artico… - British journal of …, 2001 - Wiley Online Library
Human natural killer (NK) cells constitutively express the β‐and γ‐chains of the interleukin 2
(IL‐2)/IL‐15 receptor, and both IL‐2 and IL‐15 are able to activate NK cell proliferation and …

Nonspecific cytotoxic cells and innate immunity: regulation by programmed cell death

DL Evans, JH Leary III, L Jaso-Friedmann - Developmental & Comparative …, 2001 - Elsevier
Although programmed cell death (PCD) and the cellular pathology of apoptosis have been
extensively studied in mammals and invertebrates, little is known regarding these important …

Depletion of NK cells attenuates paraquat-induced acute lung injury by manipulating macrophage polarization

M Wu, C Zhou, M Li, H Yu, D Zhao, W Xue, L Qin… - International …, 2020 - Elsevier
Acute lung injury is the main causative factor in paraquat dichloride (PQ)-induced mortality.
The innate immune system-triggered detrimental inflammatory cascade plays a vital role in …