[HTML][HTML] Association between obstructive sleep apnea and heart failure in adults—a systematic review

A Polecka, N Olszewska, Ł Danielski… - Journal of clinical …, 2023 - mdpi.com
Background: Heart failure (HF) patients commonly experience obstructive sleep apnea
(OSA), which may worsen their condition. We reviewed a diverse range of studies to …

[HTML][HTML] The pathogenesis of central and complex sleep apnea

EG Roberts, JR Raphelson, JE Orr… - Current neurology and …, 2022 - Springer
Purpose The purpose of this article is to review the recent literature on central apnea. Sleep
disordered breathing (SDB) is characterized by apneas (cessation in breathing), and …

Chemoreflex and baroreflex sensitivity hold a strong prognostic value in chronic heart failure

A Giannoni, F Gentile, F Buoncristiani, C Borrelli… - Heart Failure, 2022 - jacc.org
Background Novel treatments targeting in baroreflex sensitivity (BRS) and chemoreflex
sensitivity (CRS) heart failure (HF) are grounded on small prognostic studies, partly …

[HTML][HTML] Impact of sacubitril/valsartan on surfactant binding proteins, central sleep apneas, lung function tests and heart failure biomarkers: hemodynamic or …

M Mapelli, I Mattavelli, E Salvioni, C Banfi… - Frontiers in …, 2022 - frontiersin.org
Purpose Little is known about the mechanism underlying Sacubitril/Valsartan effects in
patients with heart failure (HFrEF). Aim of the study is to assess hemodynamic vs. non …

[HTML][HTML] Effects of sacubitril-valsartan on clinical, echocardiographic, and polygraphic parameters in patients affected by heart failure with reduced ejection fraction and …

C Pelaia, G Armentaro, M Volpentesta… - Frontiers in …, 2022 - frontiersin.org
Background Heart failure with reduced ejection fraction (HFrEF) is a clinical condition
frequently diagnosed in clinical practice. In patients affected by HFrEF, sleep apnea (SA) …

[HTML][HTML] Effects of sacubitril/valsartan on life quality in chronic heart failure: A systematic review and meta-analysis of randomized controlled trials

Y Song, Z Zhao, J Zhang, F Zhao, P Jin - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Aims Sacubitril/valsartan has been demonstrated to have cardiovascular benefits in patients
with chronic heart failure (CHF). We aimed to conduct a meta-analysis of its effects on life …

[HTML][HTML] Effects of sacubitril-valsartan on central and obstructive apneas in heart failure patients with reduced ejection fraction

Y Wang, RF Branco, M Salanitro, T Penzel… - Sleep and …, 2023 - Springer
Objective This study aimed to evaluate the effect of sacubitril-valsartan (SV) on central
apneas (CA) and obstructive apneas (OA) in patients with heart failure with reduced ejection …

[HTML][HTML] Impact of sacubitril/valsartan on cardiac and systemic hypoxia in chronic heart failure

H Nougué, F Picard, A Cohen-Solal, D Logeart… - Iscience, 2024 - cell.com
In heart failure patients with reduced ejection fraction, Sacubitril/valsartan (S/V) increased
proBNP T71 glycosylation, which is regulated negatively by hypoxia via miR-30a in vitro …

Sleep outcomes from AWAKE-HF: a randomized clinical trial of sacubitril/valsartan vs enalapril in patients with heart failure and reduced ejection fraction

RL Owens, K Birkeland, JT Heywood… - Journal of Cardiac …, 2021 - Elsevier
Background Heart failure and sleep-disordered breathing have been increasingly
recognized as co-occurring conditions. Their bidirectional relationship warrants investigation …

Central sleep apnea: treating the epiphenomenon and neglecting the disease?

E Perger, M Arzt - Sleep, 2023 - academic.oup.com
Central sleep apnea (CSA) has always been a challenge to diagnose and treat. Especially
patients with fluid overload, such as patients with heart failure (HF) present with CSA [1]. In …