[HTML][HTML] Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility

NL Smith, AL Wilson, J Gandhi, S Vatsia… - Medical gas …, 2017 - journals.lww.com
The use of ozone (O 3) gas as a therapy in alternative medicine has attracted skepticism due
to its unstable molecular structure. However, copious volumes of research have provided …

[HTML][HTML] Oxygen–Ozone therapy in the rehabilitation field: state of the art on mechanisms of action, safety andeffectiveness in patients with musculoskeletal disorders

A de Sire, F Agostini, L Lippi, M Mangone, S Marchese… - Biomolecules, 2021 - mdpi.com
In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably
increased in the field of rehabilitation. Despite its widespread use in common clinical …

[HTML][HTML] The role of Nrf2 in the antioxidant cellular response to medical ozone exposure

M Galiè, V Covi, G Tabaracci, M Malatesta - International Journal of …, 2019 - mdpi.com
Ozone (O3) is a natural, highly unstable atmospheric gas that rapidly decomposes to
oxygen. Although not being a radical molecule, O3 is a very strong oxidant and therefore it is …

[HTML][HTML] The biochemical and pharmacological properties of ozone: the smell of protection in acute and chronic diseases

R Di Mauro, G Cantarella, R Bernardini… - International journal of …, 2019 - mdpi.com
Ozone therapy has been widely used in everyday clinical practice over the last few years,
leading to significant clinical results in the treatment of herniated discs and pain …

[HTML][HTML] Clinical utility of ozone therapy for musculoskeletal disorders

O Seyam, NL Smith, I Reid, J Gandhi, W Jiang… - Medical gas …, 2018 - journals.lww.com
Abstract Oxygen-ozone (O 3) therapy serves as an alternative medical technique that
increases the oxygen in the body along with the introduction of O 3. O 3 therapy has finally …

The usefulness of ozone treatment in spinal pain

V Bocci, E Borrelli, I Zanardi… - Drug design, development …, 2015 - Taylor & Francis
Objective The aim of this review is to elucidate the biochemical, molecular, immunological,
and pharmaceutical mechanisms of action of ozone dissolved in biological fluids. Studies …

[HTML][HTML] The role of ozone treatment as integrative medicine. An evidence and gap map

MEG Serra, J Baeza-Noci, CV Mendes Abdala… - Frontiers in Public …, 2023 - frontiersin.org
Introduction The Brazil has one of the largest public health systems in the world and in the
1980's, Traditional, Complementary and Integrative Medicine were introduced. In 2018, the …

Medical ozone promotes Nrf2 phosphorylation reducing oxidative stress and pro-inflammatory cytokines in multiple sclerosis patients

L Delgado-Roche, M Riera-Romo, F Mesta… - European journal of …, 2017 - Elsevier
Oxidative stress and inflammation play key roles in the pathogenesis of Multiple sclerosis
(MS). Different drugs have been used in the clinical practice, however, there is not a …

Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain

N Braidy, M Izadi, A Sureda… - Journal of cellular …, 2018 - Wiley Online Library
Ozone, one of the most important air pollutants, is a triatomic molecule containing three
atoms of oxygen that results in an unstable form due to its mesomeric structure. It has been …

Ozone therapy for treating foot ulcers in people with diabetes

J Liu, P Zhang, J Tian, L Li, J Li… - Cochrane Database …, 2015 - cochranelibrary.com
Ozone therapy for treating foot ulcers in people with diabetes - Liu, J - 2015 | Cochrane
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