Camptothecin-based prodrug nanomedicines for cancer therapy

H Jiang, RS Zhang, C Wang, J Yu, Z Guo - Nanoscale, 2023 - pubs.rsc.org
Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication cancer cells via
blocking DNA topoisomerase 1. Despite its encouraging and wide spectrum antitumour …

Application of hyaluronic acid-based nanoparticles for cancer combination therapy

M Yang, Y Zhang, Z Hu, H Xie, W Tian, Z Liu - International Journal of …, 2023 - Elsevier
Cancer is a significant public health problem in the world. The treatment methods include
surgery, chemotherapy, phototherapy, and immunotherapy. Due to their respective …

Acid-sensitive Prodrugs; A Promising Approach for Site-specific and Targeted Drug Release

A Nazli, MZI Khan, Á Rácz, S Béni - European Journal of Medicinal …, 2024 - Elsevier
Drugs administered through conventional formulations are devoid of targeting and often
spread to various undesired sites, leading to sub-lethal concentrations at the site of action …

Recent advances and applications of nitroreductase activable agents for tumor theranostic

B Shang, Z Yu, Z Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
Nitroreductase activable agents offer a personalized and targeted approach to cancer
theranostics by selectively activating prodrugs within the tumor microenvironment. These …

A self-assembly active nanomodulator based on berberine for photothermal immunotherapy of breast cancer via dual regulation of immune suppression

J Sun, T Ye, XX Chen, B Li, Y Wei, H Zheng… - International Journal of …, 2024 - Elsevier
Breast cancer (BC) remains a significant global health concern, especially affecting women,
necessitating the development of effective treatment strategies. Photothermal …

Co-assembly of cisplatin and dasatinib in hyaluronan nanogel to combat triple negative breast cancer with reduced side effects

R Liu, W Hou, J Li, X Gou, M Gao, H Wang… - International Journal of …, 2024 - Elsevier
Abstract Treatment for triple negative breast cancer (TNBC) remains a huge challenge due
to the lack of targeted therapeutics and tumor heterogenicity. Cisplatin (Cis) have …

A tumor-targeted and enzyme-responsive gold nanorod-based nanoplatform with facilitated endo–lysosomal escape for synergetic photothermal therapy and protein …

B Wang, XJ Xu, Y Fu, B Ren, XD Yang, HY Yang - Dalton Transactions, 2024 - pubs.rsc.org
To tackle the obstacles related to tumor targeting and overcome the limitations of single
treatment models, we have developed a nanoplatform that is both tumor-targeted and …

Metal‐Organic Framework‐Based Nanomedicines for Ferroptotic Cancer Therapy

Y Song, X Xu, Z Wang, Y Zhao - Advanced Healthcare …, 2024 - Wiley Online Library
As an iron‐dependent, non‐apoptosis, regulated cell death (RCD) modality, ferroptosis has
gained growing attention for cancer therapy. With the development of nanomaterials in the …

Redox-responsive hyaluronic acid-celastrol prodrug micelles with glycyrrhetinic acid co-delivery for tumor combination therapy

L Fu, Z Su, S Wu, Y Cheng, C Hu, J Zhang - Chinese Chemical Letters, 2024 - Elsevier
Combining cytotoxic drugs with tumor microenvironment (TME) modulator agents is an
effective strategy to enhance anti-tumor effects. In this study, two natural anti-tumor active …

Fe-Co/ZIF-8@ SLC-0111-HA 复合纳米平台加强肿瘤化学动力学的可行性

王振鑫, 周鹏, 褚福超, 张大振, 袁峰 - 中国组织工程研究, 2024 - cjter.com
Fe-Co/ZIF-8@SLC-0111-HA复合纳米平台加强肿瘤化学动力学的可行性 中国组织工程研究 首页
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