[HTML][HTML] Safety and Efficacy of Antiviral Drugs and Vaccines in Pregnant Women: Insights from Physiologically Based Pharmacokinetic Modeling and Integration of …
B Costa, MJ Gouveia, N Vale - Vaccines, 2024 - mdpi.com
Addressing the complexities of managing viral infections during pregnancy is essential for
informed medical decision-making. This comprehensive review delves into the management …
informed medical decision-making. This comprehensive review delves into the management …
Research landscape of physiologically based pharmacokinetic model utilization in different fields: a bibliometric analysis (1999–2023)
X Wang, J Wu, H Ye, X Zhao, S Zhu - Pharmaceutical Research, 2024 - Springer
Purpose The physiologically based pharmacokinetic (PBPK) modeling has received
increasing attention owing to its excellent predictive abilities. However, there has been no …
increasing attention owing to its excellent predictive abilities. However, there has been no …
Dose Optimization Informed by PBPK Modeling: State‐of‐the Art and Future
K Rowland Yeo, E Gil Berglund, Y Chen - Clinical Pharmacology & … - Wiley Online Library
Model‐informed drug development (MIDD) is a powerful quantitative approach that plays an
integral role in drug development and regulatory review. While applied throughout the life …
integral role in drug development and regulatory review. While applied throughout the life …
[引用][C] EMA perspective on the value of model‐informed drug development for labeling recommendations regarding medicine use during pregnancy and …
E Manolis, FT Musuamba, CS de Vries… - CPT …, 2024 - Wiley Online Library
Except for medicines intended for use in pregnancy, pregnant and breastfeeding individuals
are routinely excluded from drug development programs. Consequently, when medicines …
are routinely excluded from drug development programs. Consequently, when medicines …