The transition from genomics to phenomics in personalized population health

JT Yurkovich, SJ Evans, N Rappaport, JL Boore… - Nature Reviews …, 2024 - nature.com
Modern health care faces several serious challenges, including an ageing population and
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …

[HTML][HTML] The impact of obesity and lifestyle on the immune system and susceptibility to infections such as COVID-19

DL De Frel, DE Atsma, H Pijl, JC Seidell… - Frontiers in …, 2020 - frontiersin.org
Background–COVID-19 is a global challenge to healthcare. Obesity is common in patients
with COVID-19 and seems to aggravate disease prognosis. In this review we explore the link …

Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease

N Wang, Y Sun, H Zhang, B Wang, C Chen… - European heart …, 2021 - academic.oup.com
Aims The aim of this study was to test whether current and past night shift work was
associated with incident atrial fibrillation (AF) and whether this association was modified by …

[HTML][HTML] Cardiovascular disease prevention and management in the COVID-19 era and beyond: an international perspective

MA Faghy, J Yates, AP Hills, S Jayasinghe… - Progress in …, 2023 - Elsevier
Despite some indicators of a localized curtailing of cardiovascular disease (CVD)
prevalence, CVD remains one of the largest contributors to global morbidity and mortality …

Diabetes and cardiometabolic risk in South Asian youth: A review

RM Wolf, M Nagpal, SN Magge - Pediatric diabetes, 2021 - Wiley Online Library
South Asians are at increased risk for developing type 2 diabetes and cardiovascular
disease at lower body mass index compared to other ancestral groups. Many factors …

[HTML][HTML] Interplay between fatty acid desaturase2 (FADS2) rs174583 genetic variant and dietary antioxidant capacity: cardio-metabolic risk factors in obese …

M Khodarahmi, P Javidzade, MA Farhangi… - BMC Endocrine …, 2022 - Springer
Objective Polymorphisms of the fatty acid desaturase (FADS) gene cluster have been
associated with obesity and its-related consequences. This cross-sectional study aimed to …

[HTML][HTML] Interactions between genetic and lifestyle factors on cardiometabolic disease-related outcomes in Latin American and Caribbean populations: A systematic …

R Wuni, EF Ventura, K Curi-Quinto, C Murray… - Frontiers in …, 2023 - frontiersin.org
Introduction The prevalence of cardiometabolic diseases has increased in Latin American
and the Caribbean populations (LACP). To identify gene-lifestyle interactions that modify the …

Prevalence of Cardiovascular Diseases in South Asians: Scrutinizing Traditional Risk Factors and Newly Recognized Risk Factors Sarcopenia and Osteopenia …

HK Bhotla, A Meyyazhagan, K Pushparaj… - Current Problems in …, 2024 - Elsevier
One of the primary reasons for complications and death worldwide are cardiovascular
diseases (CVDs), with a death toll of approximately 18 million per year. CVDs include …

Effects of two potential probiotic Lactobacillus bacteria on adipogenesis in vitro

D Guha, R Mukherjee, P Aich - Life Sciences, 2021 - Elsevier
Aims Overweight is a major global health problem. Various methodologies to get rid of the
extra fat are available, but usually, those are associated with adverse side effects. Probiotics …

[HTML][HTML] In vivo anti-obesity effects of Monascus pigment threonine derivative with enhanced hydrophilicity

D Choe, H Jang, HH Jung, CS Shin… - Journal of Functional …, 2020 - Elsevier
The hydrophobicity and anti-obesity characteristics of the threonine (Thr) derivative of
Monascus pigment were determined and compared with 2-(p-tolyl)-ethylamine (TEA) and …