Immature platelet dynamics are associated with clinical outcomes after major trauma
H Schofield, A Rossetto, PC Armstrong, HE Allan… - Journal of Thrombosis …, 2024 - Elsevier
Background Major trauma results in dramatic changes in platelet behavior. Newly formed
platelets are more reactive than older platelets, but their contributions to hemostasis and …
platelets are more reactive than older platelets, but their contributions to hemostasis and …
[HTML][HTML] Reticulated platelets are increased and hyper-activated in patients with cirrhosis, especially those with poor outcome
A Zanetto, S Toffanin, E Campello, CM Radu… - Digestive and Liver …, 2024 - Elsevier
Abstract Background Reticulated platelets (RePLT) are emergency circulating platelets
released to contrast peripheral platelet destruction. Aim We conducted a prospective study …
released to contrast peripheral platelet destruction. Aim We conducted a prospective study …
Causal relationship between physical activity and platelet traits: a Mendelian randomization study
M Jia, Z Wang, F Hu - Frontiers in Physiology, 2024 - frontiersin.org
Introduction: The purpose of this study was to discuss the causal relationship between
physical activity and platelet traits. Methods: A dataset from a large-scale European physical …
physical activity and platelet traits. Methods: A dataset from a large-scale European physical …
Anagrelide alleviates myocardial ischaemia–reperfusion injury by inhibiting reticulated platelets
P Zhang, H Xu, X Zhao, Z Qi, Y Yao, Q Zhao, P Sun… - Medical …, 2023 - Elsevier
Ischaemia–reperfusion injury (IRI) has been a major challenge during acute coronary
syndrome (ACS) with reperfusion therapy. But despite consistent therapeutic improvements …
syndrome (ACS) with reperfusion therapy. But despite consistent therapeutic improvements …
[HTML][HTML] Heterogeneity of platelets and their responses
S Thomas, S Kelliher, A Krishnan - Research and Practice in Thrombosis …, 2024 - Elsevier
There has been increasing recognition of heterogeneity in blood platelets and their
responses, particularly in recent years where next-generation technologies, and advanced …
responses, particularly in recent years where next-generation technologies, and advanced …
The shear rate promotes pinocytosis of extracellular dextran in platelets
M Inoue, M Ohwada… - Clinical Hemorheology and …, 2024 - content.iospress.com
BACKGROUND: Several conventional studies focused on platelet pinocytosis for possible
utilization as drug delivery systems. Although platelet pinocytosis is important in such …
utilization as drug delivery systems. Although platelet pinocytosis is important in such …
Multi-parameter phenotyping of platelets and characterisation of the effects of agonists using machine learning
A Vadgama, J Boot, HE Allan, CA Mein, PC Armstrong… - bioRxiv, 2023 - biorxiv.org
Background: Platelets are crucial for thrombosis and haemostasis, with their function driven
by the expression of specialised surface markers. The concept of distinct circulating sub …
by the expression of specialised surface markers. The concept of distinct circulating sub …
Genotyping of Platelet Alloantigens by DNA Sequencing in Pakistani Population
Introduction: Single-nucleotide polymorphism (SNP) in human platelet antigens (HPAs)
glycoproteins leads to alloimmunizations and platelet disorders such as posttransfusion …
glycoproteins leads to alloimmunizations and platelet disorders such as posttransfusion …
Assessing the immunomodulatory and haemostatic role of platelets in the type 2 inflammatory response to Schistosoma mansoni
J Greenman - 2023 - etheses.whiterose.ac.uk
Beyond their role in haemostasis, platelets have been shown to be strongly
immunomodulatory, particularly in type 1 inflammatory responses to bacteria and viruses …
immunomodulatory, particularly in type 1 inflammatory responses to bacteria and viruses …