[HTML][HTML] Recent updates on source, biosynthesis, and therapeutic potential of natural flavonoid luteolin: A review

N Muruganathan, AR Dhanapal, V Baskar… - Metabolites, 2022 - mdpi.com
Nature gives immense resources that are beneficial to humankind. The natural compounds
present in plants provide primary nutritional values to our diet. Apart from food, plants also …

[HTML][HTML] Immunopharmacological activities of luteolin in chronic diseases

L Huang, MY Kim, JY Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

Dietary luteolin: A narrative review focusing on its pharmacokinetic properties and effects on glycolipid metabolism

Z Wang, M Zeng, Z Wang, F Qin… - Journal of agricultural …, 2021 - ACS Publications
Luteolin, a flavone subclass of flavonoids, is commonly found in food plants and has multiple
biological activities. Recently, evidence is growing with regard to the potential of luteolin …

[HTML][HTML] L-Theanine: A Unique Functional Amino Acid in Tea (Camellia sinensis L.) With Multiple Health Benefits and Food Applications

MY Li, HY Liu, DT Wu, A Kenaan, F Geng, HB Li… - Frontiers in …, 2022 - frontiersin.org
Tea (Camellia sinensis L.) is a very popular health drink and has attracted increasing
attention in recent years due to its various bioactive substances. Among them, L-theanine, a …

Protection against Alzheimer's disease by luteolin: Role of brain glucose regulation, anti‐inflammatory activity, and the gut microbiota‐liver‐brain axis

JW Daily, S Kang, S Park - Biofactors, 2021 - Wiley Online Library
Luteolin is a widely distributed flavone herbs and vegetables. It has anti‐oxidant and anti‐
inflammatory activities and improves glucose metabolism by potentiating insulin sensitivity …

Paving Luteolin Therapeutic Potentialities and Agro‐Food‐Pharma Applications: Emphasis on In Vivo Pharmacological Effects and Bioavailability Traits

Y Taheri, J Sharifi-Rad, G Antika… - Oxidative Medicine …, 2021 - Wiley Online Library
Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As
many other natural flavonoids, it is often found in combination with glycosides in many fruits …

The pivotal role of JAK/STAT and IRS/PI3K signaling pathways in neurodegenerative diseases: Mechanistic approaches to polyphenols and alkaloids

L Kooshki, SN Zarneshan, S Fakhri, SZ Moradi… - Phytomedicine, 2023 - Elsevier
Abstract Background Neurodegenerative diseases (NDDs) are characterized by progressive
neuronal dysfunctionality which results in disability and human life-threatening events. In …

[HTML][HTML] Exploring the therapeutic potential of phytochemicals in Alzheimer's disease: Focus on polyphenols and monoterpenes

I Piccialli, V Tedeschi, L Caputo, S D'Errico… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a chronic, complex neurodegenerative disorder mainly
characterized by the irreversible loss of memory and cognitive functions. Different …

Dopamine beta‐hydroxylase and its genetic variants in human health and disease

E Gonzalez‐Lopez, KE Vrana - Journal of neurochemistry, 2020 - Wiley Online Library
Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme
that catalyzes the formation of norepinephrine (NE) from dopamine and has been …

Ketone production by ketogenic diet and by intermittent fasting has different effects on the gut microbiota and disease progression in an Alzheimer's disease rat model

S Park, T Zhang, X Wu, JY Qiu - Journal of clinical biochemistry and …, 2020 - jstage.jst.go.jp
Here, we hypothesized that the ketone producing regimens modulated cognitive impairment,
glucose metabolism, and inflam mation while altering the gut microbiome. The hypothesis …