Enteric glial biology, intercellular signalling and roles in gastrointestinal disease

L Seguella, BD Gulbransen - Nature reviews Gastroenterology & …, 2021 - nature.com
One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …

Enteroendocrine cells: sensing gut microbiota and regulating inflammatory bowel diseases

Y Yu, W Yang, Y Li, Y Cong - Inflammatory bowel diseases, 2020 - academic.oup.com
Host sensing in the gut microbiota has been crucial in the regulation of intestinal
homeostasis. Although inflammatory bowel diseases (IBDs), multifactorial chronic …

[HTML][HTML] Protective role of berberine on ulcerative colitis through modulating enteric glial cells–intestinal epithelial cells–immune cells interactions

H Li, C Fan, H Lu, C Feng, P He, X Yang… - … Pharmaceutica Sinica B, 2020 - Elsevier
Ulcerative colitis (UC) manifests as an etiologically complicated and relapsing
gastrointestinal disease. The enteric nervous system (ENS) plays a pivotal role in rectifying …

Antibiotic treatment-induced dysbiosis differently affects BDNF and TrkB expression in the brain and in the gut of juvenile mice

M Bistoletti, V Caputi, N Baranzini, N Marchesi… - PLoS …, 2019 - journals.plos.org
Antibiotic use during adolescence may result in dysbiosis-induced neuronal vulnerability
both in the enteric nervous system (ENS) and central nervous system (CNS) contributing to …

Enteric glia: a new player in abdominal pain

W Morales-Soto, BD Gulbransen - Cellular and molecular gastroenterology …, 2019 - Elsevier
Chronic abdominal pain is the most common gastrointestinal issue and contributes to the
pathophysiology of functional bowel disorders and inflammatory bowel disease. Current …

Visceral sensitivity modulation by faecal microbiota transplantation: the active role of gut bacteria in pain persistence

E Lucarini, V Di Pilato, C Parisio, L Micheli, A Toti… - Pain, 2022 - journals.lww.com
Recent findings linked gastrointestinal disorders characterized by abdominal pain to gut
microbiota composition. The present work aimed to evaluate the power of gut microbiota as …

[HTML][HTML] Intestinal epithelial barrier and neuromuscular compartment in health and disease

V D'Antongiovanni, C Pellegrini, M Fornai… - World Journal of …, 2020 - ncbi.nlm.nih.gov
A number of digestive and extra-digestive disorders, including inflammatory bowel diseases,
irritable bowel syndrome, intestinal infections, metabolic syndrome and neuropsychiatric …

Possible molecular mediators involved and mechanistic insight into fibromyalgia and associated co-morbidities

L Singh, A Kaur, MS Bhatti, R Bhatti - Neurochemical research, 2019 - Springer
Fibromyalgia is a chronic complex syndrome of non-articulate origin characterized by
musculoskeletal pain, painful tender points, sleep problems and co-morbidities including …

[HTML][HTML] Growth faltering regardless of chronic diarrhea is associated with mucosal immune dysfunction and microbial dysbiosis in the gut lumen

NS Rhoades, SM Hendrickson, K Prongay, A Haertel… - Mucosal …, 2021 - Elsevier
Despite the impact of childhood diarrhea on morbidity and mortality, our understanding of its
sequelae has been significantly hampered by the lack of studies that examine samples …

Fusobacterium nucleatum Causes Microbial Dysbiosis and Exacerbates Visceral Hypersensitivity in a Colonization-Independent Manner

X Gu, L Song, L Li, T Liu, M Zhang, Z Li… - Frontiers in …, 2020 - frontiersin.org
Background: Microbial dysbiosis is closely associated with visceral hypersensitivity and is
involved in the pathogenesis of irritable bowel syndrome (IBS), but the specific strains that …