Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …

Growth and differentiation factor 15 (GDF15) is a member of the transforming growth factor‐β
(TGF‐β) superfamily. GDF15 has been linked with several metabolic syndrome pathologies …

Over 650 million adults are obese (body mass index≥ 30 kg/m2) worldwide. Obesity is
commonly associated with several comorbidities, including cardiovascular disease and type …

Obesity is a syndemia that promotes high expenditures for public health, and is defined by
the excess of adipose tissue that is classified according to its function and anatomical …

Adipokines are essential mediators produced by adipose tissue and exert multiple biological
functions. In particular, adiponectin, leptin, resistin, IL-6, MCP-1 and PAI-1 play specific roles …

Prokineticins are a new class of chemokine-like peptides involved in a wide range of
biological and pathological activities. In particular, prokineticin 2 (PK2), prokineticin receptor …

Background Sustained activation of EGF receptor (EGFR) in proximal tubule cells is a
hallmark of progressive kidney fibrosis after AKI and in CKD. However, the molecular …

The maternal immune system is going through considerable changes during pregnancy.
However, little is known about the determinants of the inflammatory proteome and its relation …

The growing obesity epidemic is becoming a major public health concern, and the
associated costs represent a considerable burden on societies. Among the most common …

Context Adipose tissue distribution is a key factor influencing metabolic health and risk in
obesity-associated comorbidities. Objective Here we aim to compare the proteomic profiles …