Helicobacter pylori is a class one carcinogen which causes chronic atrophic gastritis, gastric
intestinal metaplasia, dysplasia and adenocarcinoma. The mechanisms by which H. pylori …

Dysregulation of transcription factors is one of the common problems in the pathogenesis of
human cancer. Among them, SOX9 is one of the critical transcription factors involved in …

Gastric adenocarcinoma (GAC) is the third leading cause of cancer-related death worldwide.
A high mortality rate and resistance to treatment protocols due to a heterogeneous …

From a global perspective, gastric cancer (GC) persists as a significant healthcare issue. In
the Western world, the majority of cases are discovered at late stages, when the treatment is …

Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence
and development are closely related to epigenetic modifications. Methylation of DNA before …

Gastric cancer is the most common gastrointestinal tumor with an increasing incidence.
Furthermore, advanced gastric cancer is more common, but the mechanism underlying the …

Pancreatic cancer (PC) is recognized as the most aggressive and deadliest malignancy
because it has the highest mortality of all cancers in humans. Mutations in multiple tumor …

Abnormal DNA methylation, an epigenetic modification, has increasingly been linked to the
pathogenesis of many human cancers. However, there has been little focus on the DNA …

Virulence factor gamma-glutamyltransferase (GGT) of H. pylori consumes glutamine (Gln) in
the stomach to decrease the tricarboxylic acid metabolite alpha-ketoglutarate (α-kg) and …

Higher methylation levels of RNA-binding protein for multiple splicing 2 (RBPMS2) was
reported to be related with unfavorable outcome in gastric cancer (GC). However, molecular …