Overall and comparative safety of biologic and immunosuppressive therapy in inflammatory bowel diseases

A Holmer, S Singh - Expert review of clinical immunology, 2019 - Taylor & Francis
Introduction: Efficacy and safety are key aspects when choosing therapies for patients with
inflammatory bowel diseases (IBD). While several randomized trials and indirect …

Cytokine dynamics and targeted immunotherapies in autoimmune encephalitis

NL Ciano-Petersen, S Muñiz-Castrillo… - Brain …, 2022 - academic.oup.com
Autoimmune encephalitides constitute a diverse group of immune-mediated central nervous
system disorders mainly characterized by the presence of antibodies targeting neuronal or …

Challenges in the treatment of psoriasis with biologics: vaccination, history of malignancy, human immunodeficiency virus (HIV) infection, and pediatric psoriasis

KM Plachouri, S Georgiou - International Journal of …, 2019 - Wiley Online Library
Biologics are potent immunomodulatory drugs, whose application in the treatment of
psoriasis has shown extremely good therapeutic results and a satisfactory safety profile. The …

Inhibition of interleukin‐12 and/or interleukin‐23 for the treatment of psoriasis: What is the evidence for an effect on malignancy?

EN Ergen, N Yusuf - Experimental dermatology, 2018 - Wiley Online Library
Immune cells and cytokines play an important role in the pathogenesis of psoriasis.
Interleukin‐12 (IL‐12) and IL‐23 promote cellular responses mediated by T cells, which …

The value of case reports and spontaneous reporting systems for pharmacovigilance and clinical practice

E Raschi, M La Placa, E Poluzzi… - British Journal of …, 2021 - academic.oup.com
DEAR EDITOR, We greatly appreciate a recent editorial remarking on the value of published
case reports in drug safety. It underlines the too often overlooked importance of reporting …

[PDF][PDF] Ustekinumab-induced chronic lymphocytic leukemia in a patient with psoriatic arthritis

F Gediz, MC Ugur, M Turkmen, S Kobak - Reumatologia/Rheumatology, 2021 - termedia.pl
Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by skin and joint
involvement. The disease may present with various joint pattern involvement, which …

Fifty‐two words for snow: dermatologists naming epidermal naevi

S Asch, JL Sugarman - British Journal of Dermatology, 2018 - academic.oup.com
DEAR EDITOR, In the April 2017 issue of the BJD, Kuentz et al. report an FGFR2 mutation in
a subtype of naevus sebaceus (NS). 1 On review of the histopathology, we question the …

[HTML][HTML] A case report of Hodgkin lymphoma in a patient treated with ustekinumab for psoriasis

E Charakopoulos, I Spyrou, NA Viniou… - Medicine, 2020 - journals.lww.com
Interventions: Ustekinumab administration was discontinued. The patient received treatment
with the ABVD regimen. Outcomes: The patient's disease was refractory to the above …

[PDF][PDF] Klinische Ergebnisse einer Therapie mit dem monoklonalen Anti-Interleukin-12/23-Antikörper Ustekinumab bei therapierefraktärer und therapieintoleranter …

S Janelidze - 2023 - edoc.ub.uni-muenchen.de
Zahlreiche Beschreibungen von Krankheitsbildern aus früheren Jahrhunderten könnten
einer CED entsprechen. Der Arzt Wilhelm Fabry berichtete 1612 über die Autopsie eines …

Ewing's sarcoma in a patient with Crohn's disease treated with Ustekinumab: a case report

RR Rao, F Majlessipour, DA Ziring… - Journal of Adolescent …, 2021 - liebertpub.com
Biologic therapies have revolutionized the treatment of immune-mediated diseases. They
are generally well tolerated; however, there are reports of malignancies associated with the …