[HTML][HTML] Characterization of a novel inhibitor for the New Delhi metallo-β-lactamase-4: Implications for drug design and combating bacterial drug resistance
The bacterial metallo-β-lactamases (MBLs) catalyze the inactivation of β-lactam antibiotics.
Identifying novel pharmacophores remains crucial for the clinical development of additional …
Identifying novel pharmacophores remains crucial for the clinical development of additional …
[HTML][HTML] Camel-Derived Nanobodies as Potent Inhibitors of New Delhi Metallo-β-Lactamase-1 Enzyme
R Ben Abderrazek, E Hamdi, A Piccirilli, S Dhaouadi… - Molecules, 2024 - mdpi.com
The injudicious usage of antibiotics during infections caused by Gram-negative bacteria
leads to the emergence of β-lactamases. Among them, the NDM-1 enzyme poses a serious …
leads to the emergence of β-lactamases. Among them, the NDM-1 enzyme poses a serious …
Structural insight into the subclass B1 metallo-β-lactamase AFM-1
W Niu, R Ti, D Li, R Dong, J Dong, Y Ye, Y Xiao… - Biochemical and …, 2024 - Elsevier
The emergence of drug-resistant bacteria, facilitated by metallo-beta-lactamases (MBLs),
presents a significant obstacle to the effective use of antibiotics in the management of …
presents a significant obstacle to the effective use of antibiotics in the management of …
[HTML][HTML] A Natural Novel Mutation in the blaNDM-5 Promoter Reducing Carbapenems Resistance in a Clinical Escherichia coli Strain
Y Li, R Zhang, S Wang - Microbiology Spectrum, 2022 - Am Soc Microbiol
The worldwide emergence of New Delhi metallo-b-lactamase (NDM) is of great concern.
NDM could hydrolyze almost all b-lactam antibiotics, compromising antimicrobial treatments …
NDM could hydrolyze almost all b-lactam antibiotics, compromising antimicrobial treatments …
[HTML][HTML] The in vitro inhibitory activity of polypyridine ligands towards subclass B1 metallo-β-lactamases
L Basile, A Piccirilli, F Brisdelli, M Perilli, N Bognanni… - Results in …, 2023 - Elsevier
Antimicrobial resistance leads to the ineffectiveness of antimicrobials, hampering the ability
to cure infections. Zinc-dependent metallo ß-lactamases (MBLs) producing bacteria …
to cure infections. Zinc-dependent metallo ß-lactamases (MBLs) producing bacteria …
[PDF][PDF] Results in Chemistry
AS Basaleh, HB Howsaui, AA Sharfalddin, MA Hussien - researchgate.net
New transition metal complexes were prepared from Schiff base ligands derived from
bromo/nitro salicylaldehyde derivatives and pyrazine have the general formula M [4-bromo …
bromo/nitro salicylaldehyde derivatives and pyrazine have the general formula M [4-bromo …