Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Severe acute respiratory syndrome coronavirus 2 causes direct damage to the airway
epithelium, enabling aspergillus invasion. Reports of COVID-19-associated pulmonary …

Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Aspergillosis refers to a spectrum of illness that is dependent on host factors and the
immunologic response. Noninvasive forms include allergic bronchopulmonary aspergillosis …

Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …

Background Voriconazole has been recommended as primary treatment for patients with
invasive aspergillosis. Intravenous and tablet formulations of posaconazole that have …

Despite major advances in prevention and treatment, FN remains one of the most frequent
and serious complications of cancer chemotherapy (ChT). It is a major cause of morbidity …