Platinum-based chemotherapeutics are widely used for cancer treatment but are frequently
limited because of dosage-dependent side effects and drug resistance. To attenuate these …

Mutations in the estrogen receptor alpha gene (ESR1) can lead to resistance to endocrine
therapy (ET) in hormone receptor-positive (HR+)/HER2-metastatic breast cancer (MBC) …

Despite treatment advances, breast cancer remains a leading cause of death of women in
the United States, mostly due to metastatic disease. Bone is a preferential site for breast …

PURPOSE To guide clinicians and policymakers in three global resource-constrained
settings on treating patients with metastatic breast cancer (MBC) when Maximal setting …

Importance Approximately 45% to 60% of hormone receptor (HR)–positive metastatic breast
cancer (mBC) shows a low-level expression ofERBB2. LowERBB2expression is defined …

The major reason for the failure of conventional therapies is the heterogeneity and
complexity of tumor microenvironments (TMEs). Many malignant tumors reprogram their …

Objective To evaluate the effect of emotional ABC theory on anxiety and depression in
young patients with breast cancer. Methods A total of 200 eligible young patients with breast …

Background: Web-based learning activities are key components of continuing medical
education (CME) for health care professionals (HCPs). However, the published outcomes of …

This manuscript describes the Advanced Breast Cancer (ABC) international consensus
guidelines updated at the last two ABC international consensus conferences (ABC 6 in …

Systemic Treatment of Patients With Metastatic Breast Cancer: ASCO Resource–Stratified
Guideline Q and A | JCO Global Oncology Skip to main content ASCO Publications …