Candidate biomarkers in psychiatric disorders: state of the field
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …
aid in objectively diagnosing patients and providing individualized treatment …
Bipolar disorder
Bipolar Disorder | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
[HTML][HTML] Circadian rhythms and mood disorders: Time to see the light
HK Dollish, M Tsyglakova, CA McClung - Neuron, 2024 - cell.com
The importance of time is ever prevalent in our world, and disruptions to the normal
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …
Bipolar disorder: An evolutionary psychoneuroimmunological approach
Bipolar disorder is a mental health disorder characterized by extreme shifts in mood, high
suicide rate, sleep problems, and dysfunction of psychological traits like self-esteem (feeling …
suicide rate, sleep problems, and dysfunction of psychological traits like self-esteem (feeling …
Genetic contributions to bipolar disorder: current status and future directions
KS O'Connell, BJ Coombes - Psychological Medicine, 2021 - cambridge.org
Bipolar disorder (BD) is a highly heritable mental disorder and is estimated to affect about 50
million people worldwide. Our understanding of the genetic etiology of BD has greatly …
million people worldwide. Our understanding of the genetic etiology of BD has greatly …
Lithium as a neuroprotective agent for bipolar disorder: an overview
ELM Ochoa - Cellular and molecular neurobiology, 2022 - Springer
Lithium (Li+) is a first option treatment for adult acute episodes of Bipolar Disorder (BD) and
for the prophylaxis of new depressed or manic episodes. It is also the preferred choice as …
for the prophylaxis of new depressed or manic episodes. It is also the preferred choice as …
Key roles of CACNA1C/Cav1. 2 and CALB1/calbindin in prefrontal neurons altered in cognitive disorders
Importance The risk of mental disorders is consistently associated with variants inCACNA1C
(L-type calcium channel Cav1. 2) but it is not known why these channels are critical to …
(L-type calcium channel Cav1. 2) but it is not known why these channels are critical to …
Therapeutic interventions to mitigate mitochondrial dysfunction and oxidative stress–induced damage in patients with bipolar disorder
S Madireddy, S Madireddy - International Journal of Molecular Sciences, 2022 - mdpi.com
Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …
Novel risk loci associated with genetic risk for bipolar disorder among Han Chinese individuals: a genome-wide association study and meta-analysis
HJ Li, C Zhang, L Hui, DS Zhou, Y Li, CY Zhang… - JAMA …, 2021 - jamanetwork.com
Importance The genetic basis of bipolar disorder (BD) in Han Chinese individuals is not fully
understood. Objective To explore the genetic basis of BD in the Han Chinese population …
understood. Objective To explore the genetic basis of BD in the Han Chinese population …