Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

A Thompson, E Di Angelantonio, N Sarwar, S Erqou… - Jama, 2008 - jamanetwork.com
Context The importance of the cholesteryl ester transfer protein (CETP) pathway in coronary
disease is uncertain. Study of CETP genotypes can help better understand the relevance of …

Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review

E Boes, S Coassin, B Kollerits, IM Heid… - Experimental …, 2009 - Elsevier
High-density lipoprotein (HDL) particles exhibit multiple antiatherogenic effects. They are
key players in the reverse cholesterol transport which shuttles cholesterol from peripheral …

Effects of polymorphisms in ABCG2, SLCO1B1, SLC10A1 and CYP2C9/19 on plasma concentrations of rosuvastatin and lipid response in Chinese patients

HK Lee, M Hu, SSH Lui, CS Ho, CK Wong… - …, 2013 - Future Medicine
Aim: This study examined whether the ABCG2 421C> A polymorphism and variants in other
genes potentially related to the pharmacokinetics of rosuvastatin influenced the plasma …

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis

GS Sagoo, I Tatt, G Salanti… - American journal of …, 2008 - academic.oup.com
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate
gene for coronary heart disease (CHD). The authors assessed associations between 7 LPL …

Common single nucleotide polymorphisms in Japanese patients with essential hypertension: aldehyde dehydrogenase 2 gene as a risk factor independent of alcohol …

P Hui, T Nakayama, A Morita, N Sato, M Hishiki… - Hypertension …, 2007 - nature.com
Essential hypertension (EH) is a multifactorial disorder determined by the interaction of
environmental and genetic factors. EH patients' responses to these factors may vary …

Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin

M Hu, B Tomlinson - Expert opinion on drug metabolism & …, 2014 - Taylor & Francis
Introduction: Statins are the cornerstone of lipid-lowering therapy to reduce the risk of
coronary heart disease. Rosuvastatin and pitavastatin are the two recently developed statins …

[HTML][HTML] Associations of the APOC3 rs5128 polymorphism with plasma APOC3 and lipid levels: a meta-analysis

Y Song, L Zhu, M Richa, P Li, Y Yang, S Li - Lipids in health and disease, 2015 - Springer
Background Studies of the association between the apolipoprotein C3 gene (APOC3)
rs5128 polymorphism and plasma levels of apolipoprotein C3 (APOC3) and lipids have …

Identification of Genetic Markers Associated With High-Density Lipoprotein-Cholesterol by Genome-Wide Screening in a Japanese Population The Suita Study

Y Hiura, CS Shen, Y Kokubo, T Okamura… - Circulation …, 2009 - jstage.jst.go.jp
Background: Recent genome-wide association studies (GWAS) have identified genes or loci
affecting lipid levels. Given the difference in allele frequencies and linkage disequilibrium …

Genetic determinants of HDL: monogenic disorders and contributions to variation

KLE Klos, IJ Kullo - Current opinion in cardiology, 2007 - journals.lww.com
The genetic control of high-density lipoprotein cholesterol level is complex. Maximizing the
utility of genetic knowledge for predicting an individual's high-density lipoprotein cholesterol …

Association between apolipoprotein C3 Sst I, T-455C, C-482T and C1100T polymorphisms and risk of coronary heart disease

B Lin, Y Huang, M Zhang, J Wang, Y Wu - BMJ open, 2014 - bmjopen.bmj.com
Objectives Apolipoprotein C3 (ApoC3) polymorphisms have been suggested to be
associated with risk of coronary heart disease (CHD). However, the results of relevant …