Cognitive Safety Data from a Randomized, Double‐Blind, Parallel‐Group, Placebo‐Controlled Phase IIb Study of the Effects of a Cannabidiol and Δ9 …

CH Domen, S Sillau, Y Liu, M Adkins… - Movement …, 2023 - Wiley Online Library
Background Cannabis is increasingly available worldwide but its impact on cognition in
Parkinson's disease (PD) is unknown. Objective Present cognitive safety data from study of …

Genetics of cannabis use in opioid use disorder: A genome-wide association and polygenic risk score study

A Hillmer, C Chawar, A Lamri, J Hudson, F Kapczinski… - Plos one, 2023 - journals.plos.org
Background Individuals with an Opioid Use Disorder (OUD) have increased rates of
cannabis use in comparison to the general population. Research on the short-and long-term …

[HTML][HTML] Gut bacteria, endocannabinoid system, and marijuana addiction: Novel therapeutic implications

KK Pinapati, S Vidya, MF Khan, D Mandal… - Health Sciences …, 2024 - Elsevier
Gut bacteria plays a leading role in the pharmacological actions of both synthetic and
natural product derived drugs. Their interactions are complex and bidirectional. This …

[HTML][HTML] Effects of cannabinoids on resting state functional brain connectivity: a systematic review

V Lorenzetti, A Gaillard, D Thomson, A Englund… - Neuroscience & …, 2023 - Elsevier
Cannabis products are widely used for medical and non-medical reasons worldwide and
vary in content of cannabinoids such as delta-9-tetrahydrocannabinol (THC) and …

Polysubstance use in early adulthood: Patterns and developmental precursors in an urban cohort

A Steinhoff, L Bechtiger, D Ribeaud… - Frontiers in Behavioral …, 2022 - frontiersin.org
Polysubstance use (ie, simultaneous or sequential use of different psychoactive substances)
is associated with increases in the risk of severe health problems and social impairments …

The effects of pelleted cannabidiol supplementation on heart rate and reaction scores in horses

AL Draeger, EP Thomas, KA Jones, AJ Davis… - Journal of Veterinary …, 2021 - Elsevier
The potential use of cannabidiol (CBD) as a nutraceutical to support improved health and
welfare has been of increasing interest. In particular, CBD has been shown to decrease …

Acute effects of cannabis on speech illusions and psychotic-like symptoms: two studies testing the moderating effects of cannabidiol and adolescence

C Mokrysz, NDC Shaban, TP Freeman… - Psychological …, 2021 - cambridge.org
BackgroundAcute cannabis administration can produce transient psychotic-like effects in
healthy individuals. However, the mechanisms through which this occurs and which factors …

Opposite roles for cannabidiol and δ-9-tetrahydrocannabinol in psychotomimetic effects of cannabis extracts: a naturalistic controlled study

A Sainz-Cort, D Jimenez-Garrido… - Journal of Clinical …, 2021 - journals.lww.com
Background Although δ-9-tetrahydrocannabinol (THC), the main cannabinoid from the
cannabis plant, is responsible for the psychotomimetic effects of cannabis, cannabidiol …

A “good” smoke? The off-label use of cannabidiol to reduce cannabis use

D Fortin, V Di Beo, S Massin, Y Bisiou, P Carrieri… - Frontiers in …, 2022 - frontiersin.org
Background Although cannabis use is common in France, it is still criminalized. Cannabidiol
(CBD) products, including CBD-rich cannabis, are legally available. Although previous …

Regulation of DNA methylation by cannabidiol and its implications for psychiatry: new insights from in vivo and in silico models

LB Domingos, NR Silva, AJM Chaves Filho, AJ Sales… - Genes, 2022 - mdpi.com
Cannabidiol (CBD) is a non-psychotomimetic compound present in cannabis sativa. Many
recent studies have indicated that CBD has a promising therapeutic profile for stress-related …